CDK4 is co-amplified with either TP53 promoter gene fusions or MDM2 through distinct mechanisms in osteosarcoma
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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1 Online-Ressource.
- Language
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Englisch
- Bibliographic citation
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CDK4 is co-amplified with either TP53 promoter gene fusions or MDM2 through distinct mechanisms in osteosarcoma ; volume:9 ; number:1 ; day:25 ; month:9 ; year:2024 ; pages:1-12 ; date:12.2024
npj Genomic Medicine ; 9, Heft 1 (25.9.2024), 1-12, 12.2024
- Creator
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Saba, Karim H.
Difilippo, Valeria
Styring, Emelie
Nilsson, Jenny
Magnusson, Linda
van den Bos, Hilda
Wardenaar, René
Spierings, Diana C. J.
Foijer, Floris
Nathrath, Michaela
Haglund de Flon, Felix
Baumhoer, Daniel
Nord, Karolin H.
- Contributor
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SpringerLink (Online service)
- DOI
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10.1038/s41525-024-00430-y
- URN
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urn:nbn:de:101:1-2412112113202.465013168392
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:30 AM CEST
Data provider
This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Saba, Karim H.
- Difilippo, Valeria
- Styring, Emelie
- Nilsson, Jenny
- Magnusson, Linda
- van den Bos, Hilda
- Wardenaar, René
- Spierings, Diana C. J.
- Foijer, Floris
- Nathrath, Michaela
- Haglund de Flon, Felix
- Baumhoer, Daniel
- Nord, Karolin H.
- SpringerLink (Online service)
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CDK4 inhibition diminishes p53 activation by MDM2 antagonists
Combined targeting of MDM2 and CDK4 is synergistic in dedifferentiated liposarcomas
Overdiagnosis of atypical lipomatous tumors/well-differentiated liposarcomas by morphological diagnosis using only HE stained specimens: a case–control study with MDM2/CDK4 immunostaining and MDM2/CDK4 fluorescence in situ hybridization
Amplification of CDK4 and MDM2: a detailed study of a high-risk neuroblastoma subgroup
PDLIM7 and CDH18 regulate the turnover of MDM2 during CDK4/6 inhibitor therapy-induced senescence
Low-Grade Uterine Adenosarcoma with Overexpression of MDM2 and CDK4 by Immunohistochemistry: A Case Report and Literature Review
MDM2 inhibition in combination with endocrine therapy and CDK4/6 inhibition for the treatment of ER-positive breast cancer
Regulation of CDK4
Fusions-Fieber
Interpolative Fusions
Impact of the MDM2 splice-variants MDM2-A, MDM2-B and MDM2-C on cytotoxic stress response in breast cancer cells
Either, Rupert
CDK4 inhibition diminishes p53 activation by MDM2 antagonists
Combined targeting of MDM2 and CDK4 is synergistic in dedifferentiated liposarcomas
Overdiagnosis of atypical lipomatous tumors/well-differentiated liposarcomas by morphological diagnosis using only HE stained specimens: a case–control study with MDM2/CDK4 immunostaining and MDM2/CDK4 fluorescence in situ hybridization
Amplification of CDK4 and MDM2: a detailed study of a high-risk neuroblastoma subgroup
PDLIM7 and CDH18 regulate the turnover of MDM2 during CDK4/6 inhibitor therapy-induced senescence
Low-Grade Uterine Adenosarcoma with Overexpression of MDM2 and CDK4 by Immunohistochemistry: A Case Report and Literature Review
MDM2 inhibition in combination with endocrine therapy and CDK4/6 inhibition for the treatment of ER-positive breast cancer
Regulation of CDK4
Fusions-Fieber
Interpolative Fusions
Impact of the MDM2 splice-variants MDM2-A, MDM2-B and MDM2-C on cytotoxic stress response in breast cancer cells