Polyphenolic Platform Ameliorated Sanshool for Skin Photoprotection
Abstract: Natural evolution has nurtured a series of active molecules that play vital roles in physiological systems, but their further applications have been severely limited by rapid deactivation, short cycle time, and potential toxicity after isolation. For instance, the instability of structures and properties has greatly descended when sanshool is derived from Zanthoxylum xanthoxylum. Herein, natural polyphenols are employed to boost the key properties of sanshool by fabricating a series of nanoparticles (NPs). The intracellular evaluation and in vivo animal model are conducted to demonstrate the decreased photodamage score and skin‐fold thickness of prepared NPs, which can be attributed to the better biocompatibility, improved free radical scavenging, down‐regulated apoptosis ratios, and reduced DNA double‐strand breaks compared to naked sanshool. This work proposes a novel strategy to boost the key properties of naturally occurring active molecules with the assistance of natural polyphenol‐based platforms.
- Location
-
Deutsche Nationalbibliothek Frankfurt am Main
- Extent
-
Online-Ressource
- Language
-
Englisch
- Bibliographic citation
-
Polyphenolic Platform Ameliorated Sanshool for Skin Photoprotection ; day:15 ; month:02 ; year:2024 ; extent:11
Advanced science ; (15.02.2024) (gesamt 11)
- Creator
-
Wang, Tianyou
Guo, Linghong
Wu, Shuwei
Xu, Yuanyuan
Song, Junmei
Yang, Yi
Zhang, Hengjie
Li, Dongcui
Li, Yiwen
Jiang, Xian
Gu, Zhipeng
- DOI
-
10.1002/advs.202310012
- URN
-
urn:nbn:de:101:1-2024021614100367045208
- Rights
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
-
15.08.2025, 7:28 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Wang, Tianyou
- Guo, Linghong
- Wu, Shuwei
- Xu, Yuanyuan
- Song, Junmei
- Yang, Yi
- Zhang, Hengjie
- Li, Dongcui
- Li, Yiwen
- Jiang, Xian
- Gu, Zhipeng
Other Objects (12)
A Learning-Based Framework for Identifying MicroRNA Regulatory Module
On a strongly damped semilinear wave equation with time-varying source and singular dissipation
Reciprocal Relationships Between Parental Involvement and Academic Performance in Early Adolescence: A Two-Year Longitudinal Study in China
PdNi Nanoframework and Nanochain Catalysts with Enhanced Oxygen Reduction Reaction Performance
Assessment of bacterial communities in skin ulceration in cultured sea cucumber Apostichopus japonicus (Selenka)
Search for axion(-like) particles in heavy-ion collisions
Confinement-deconfinement phase transition for heavy quarks in a soft wall holographic QCD model
Prediction of glycopeptide fragment mass spectra by deep learning
Spontaneous hemothorax by pulmonary arteriovenous malformation during pregnancy
Role of Tissue Hydraulic Permeability in Convection-Enhanced Delivery of Nanoparticle-Encapsulated Chemotherapy Drugs to Brain Tumour
Modifications of Prenyl Side Chains in Natural Product Biosynthesis
A Stacked Autoencoder-Based miRNA Regulatory Module Detection Framework
A Learning-Based Framework for Identifying MicroRNA Regulatory Module
On a strongly damped semilinear wave equation with time-varying source and singular dissipation
Reciprocal Relationships Between Parental Involvement and Academic Performance in Early Adolescence: A Two-Year Longitudinal Study in China
PdNi Nanoframework and Nanochain Catalysts with Enhanced Oxygen Reduction Reaction Performance
Assessment of bacterial communities in skin ulceration in cultured sea cucumber Apostichopus japonicus (Selenka)
Search for axion(-like) particles in heavy-ion collisions
Confinement-deconfinement phase transition for heavy quarks in a soft wall holographic QCD model
Prediction of glycopeptide fragment mass spectra by deep learning
Spontaneous hemothorax by pulmonary arteriovenous malformation during pregnancy
Role of Tissue Hydraulic Permeability in Convection-Enhanced Delivery of Nanoparticle-Encapsulated Chemotherapy Drugs to Brain Tumour
Modifications of Prenyl Side Chains in Natural Product Biosynthesis
A Stacked Autoencoder-Based miRNA Regulatory Module Detection Framework
A Learning-Based Framework for Identifying MicroRNA Regulatory Module
On a strongly damped semilinear wave equation with time-varying source and singular dissipation
Reciprocal Relationships Between Parental Involvement and Academic Performance in Early Adolescence: A Two-Year Longitudinal Study in China
PdNi Nanoframework and Nanochain Catalysts with Enhanced Oxygen Reduction Reaction Performance
Assessment of bacterial communities in skin ulceration in cultured sea cucumber Apostichopus japonicus (Selenka)
Search for axion(-like) particles in heavy-ion collisions
Confinement-deconfinement phase transition for heavy quarks in a soft wall holographic QCD model
Prediction of glycopeptide fragment mass spectra by deep learning
Spontaneous hemothorax by pulmonary arteriovenous malformation during pregnancy
Role of Tissue Hydraulic Permeability in Convection-Enhanced Delivery of Nanoparticle-Encapsulated Chemotherapy Drugs to Brain Tumour
Modifications of Prenyl Side Chains in Natural Product Biosynthesis