Polyphenolic Platform Ameliorated Sanshool for Skin Photoprotection
Abstract: Natural evolution has nurtured a series of active molecules that play vital roles in physiological systems, but their further applications have been severely limited by rapid deactivation, short cycle time, and potential toxicity after isolation. For instance, the instability of structures and properties has greatly descended when sanshool is derived from Zanthoxylum xanthoxylum. Herein, natural polyphenols are employed to boost the key properties of sanshool by fabricating a series of nanoparticles (NPs). The intracellular evaluation and in vivo animal model are conducted to demonstrate the decreased photodamage score and skin‐fold thickness of prepared NPs, which can be attributed to the better biocompatibility, improved free radical scavenging, down‐regulated apoptosis ratios, and reduced DNA double‐strand breaks compared to naked sanshool. This work proposes a novel strategy to boost the key properties of naturally occurring active molecules with the assistance of natural polyphenol‐based platforms.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Polyphenolic Platform Ameliorated Sanshool for Skin Photoprotection ; day:15 ; month:02 ; year:2024 ; extent:11
Advanced science ; (15.02.2024) (gesamt 11)
- Urheber
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Wang, Tianyou
Guo, Linghong
Wu, Shuwei
Xu, Yuanyuan
Song, Junmei
Yang, Yi
Zhang, Hengjie
Li, Dongcui
Li, Yiwen
Jiang, Xian
Gu, Zhipeng
- DOI
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10.1002/advs.202310012
- URN
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urn:nbn:de:101:1-2024021614100367045208
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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15.08.2025, 07:28 MESZ
Datenpartner
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Wang, Tianyou
- Guo, Linghong
- Wu, Shuwei
- Xu, Yuanyuan
- Song, Junmei
- Yang, Yi
- Zhang, Hengjie
- Li, Dongcui
- Li, Yiwen
- Jiang, Xian
- Gu, Zhipeng
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