Sharp interface analysis of a diffuse interface model for cell blebbing with linker dynamics

Abstract: We investigate the convergence of solutions of a recently proposed diffuse interface/phase field model for cell blebbing by means of matched asymptotic expansions. It is a biological phenomenon that increasingly attracts attention by both experimental and theoretical communities. Key to understanding the process of cell blebbing mechanically are proteins that link the cell cortex and the cell membrane. Another important model component is the bending energy of the cell membrane and cell cortex which accounts for differential equations up to sixth order. Both aspects pose interesting mathematical challenges that will be addressed in this work like showing non‐singularity formation for the pressure at boundary layers, deriving equations for asymptotic series coefficients of uncommonly high order, and dealing with a highly coupled system of equations.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Sharp interface analysis of a diffuse interface model for cell blebbing with linker dynamics ; day:12 ; month:09 ; year:2023 ; extent:39
ZAMM ; (12.09.2023) (gesamt 39)

Urheber
Nöldner, Philipp
Burger, Martin
Garcke, Harald

DOI
10.1002/zamm.202300101
URN
urn:nbn:de:101:1-2023091315373745654549
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
14.08.2025, 11:02 MESZ

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