Aromatic Fluorination of Multiblock Amphiphile Enhances Its Incorporation into Lipid Bilayer Membranes

Abstract: We designed multiblock amphiphiles AmF and AmH, which consist of perfluorinated and non‐fluorinated hydrophobic units, respectively. Absorption spectroscopy revealed that both amphiphiles are molecularly dispersed in organic solvent, while they form aggregates under aqueous conditions. Furthermore, we investigated whether AmF and AmH can be incorporated into DOPC lipid bilayer membranes, and found that the maximum concentration of AmF that can be incorporated into DOPC lipid bilayer membranes is 43 times higher than that of AmH.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Aromatic Fluorination of Multiblock Amphiphile Enhances Its Incorporation into Lipid Bilayer Membranes ; volume:9 ; number:3 ; year:2020 ; pages:301-303 ; extent:3
ChemistryOpen ; 9, Heft 3 (2020), 301-303 (gesamt 3)

Creator
Sasaki, Ryo
Sato, Kohei
Kinbara, Kazushi

DOI
10.1002/open.201900374
URN
urn:nbn:de:101:1-2022070211255014171157
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:27 AM CEST

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Associated

  • Sasaki, Ryo
  • Sato, Kohei
  • Kinbara, Kazushi

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