Shaping the CD4 + memory immune response against tuberculosis: the role of antigen persistence, location and multi-functionality
Abstract: Effective vaccination against intracellular pathogens, such as tuberculosis (TB), relies on the generation and maintenance of CD4 memory T cells. An incomplete understanding of the memory immune response has hindered the rational design of a new, more effective TB vaccine. This review discusses how the persistence of antigen, the location of memory cells, and their multifunctional ability shape the CD4 memory T cell response against TB.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Shaping the CD4 + memory immune response against tuberculosis: the role of antigen persistence, location and multi-functionality ; volume:3 ; number:1 ; year:2012 ; pages:13-20
Biomolecular concepts ; 3, Heft 1 (2012), 13-20
- Creator
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Ancelet, Lindsay
Kirman, Joanna
- DOI
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10.1515/bmc.2011.051
- URN
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urn:nbn:de:101:1-2409241657319.329141651087
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:33 AM CEST
Data provider
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Associated
- Ancelet, Lindsay
- Kirman, Joanna
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