Metal–Organic Framework‐Based Stimuli‐Responsive Systems for Drug Delivery

Abstract: With the rapid development of nanotechnology, stimuli‐responsive nanomaterials have provided an alternative for designing controllable drug delivery systems due to their spatiotemporally controllable properties. As a new type of porous material, metal–organic frameworks (MOFs) have been widely used in biomedical applications, especially drug delivery systems, owing to their tunable pore size, high surface area and pore volume, and easy surface modification. Here, recent progress in MOF‐based stimuli‐responsive systems is presented, including pH‐, magnetic‐, ion‐, temperature‐, pressure‐, light‐, humidity‐, redox‐, and multiple stimuli‐responsive systems for the delivery of anticancer drugs. The remaining challenges and suggestions for future directions for the rational design of MOF‐based nanomedicines are also discussed.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Metal–Organic Framework‐Based Stimuli‐Responsive Systems for Drug Delivery ; volume:6 ; number:1 ; year:2019 ; extent:20
Advanced science ; 6, Heft 1 (2019) (gesamt 20)

Creator
Cai, Wen
Wang, Junqing
Chu, Chengchao
Chen, Wei
Wu, Chunsheng
Liu, Gang

DOI
10.1002/advs.201801526
URN
urn:nbn:de:101:1-2022071508530545537639
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:32 AM CEST

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Associated

  • Cai, Wen
  • Wang, Junqing
  • Chu, Chengchao
  • Chen, Wei
  • Wu, Chunsheng
  • Liu, Gang

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