Stimuli‐Responsive New Horizons for Biomedical Applications: Metal–Organic Framework‐Based Nanozymes

Nanozymes, nanomaterials exhibiting enzyme‐mimicking activities, have gained considerable interest in biomedicine due to their stability, adjustability, and cost‐efficiency. Among these, metal–organic framework (MOF)‐based nanozymes distinguish themselves by their distinct structure and customizable characteristics. Researchers have explored MOF‐based nanozymes as a platform for developing stimuli‐responsive behaviors. This work first presents the categorization of MOF‐based nanozymes, which are designed to mimic the catalytic functions of oxidases, peroxidases, catalase, superoxide dismutase, hydrolases, and multifunctional enzymes. Crafting MOF‐based nanozymes includes customizing their reactions to particular stimuli, including pH, temperature, light, or biomolecular triggers, ensuring enhanced specificity and potency in catalytic performance amid environmental changes. Moreover, these nanozymes exhibit immense potential in biomedical applications, playing crucial roles in therapeutic interventions like cancer therapy and tissue regeneration. Finally, the article delves into future opportunities and challenges within emerging research frontiers. These stimuli‐responsive MOF‐based nanozymes offer novel avenues for advanced therapeutic strategies, providing prospects for innovative biomedical applications.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Stimuli‐Responsive New Horizons for Biomedical Applications: Metal–Organic Framework‐Based Nanozymes ; day:26 ; month:04 ; year:2024 ; extent:23
Small structures ; (26.04.2024) (gesamt 23)

Creator
Yan, Jingyu
Zhao, Yifan
Du, Meijun
Cui, Chenying
Bai, Ziyang
Liu, Yingyu
Sun, Lingxiang
Qin, Danlei
Zhou, Jian
Wu, Xiuping
Li, Bing

DOI
10.1002/sstr.202400029
URN
urn:nbn:de:101:1-2404261421255.628026181537
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
14.08.2025, 10:44 AM CEST

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Associated

  • Yan, Jingyu
  • Zhao, Yifan
  • Du, Meijun
  • Cui, Chenying
  • Bai, Ziyang
  • Liu, Yingyu
  • Sun, Lingxiang
  • Qin, Danlei
  • Zhou, Jian
  • Wu, Xiuping
  • Li, Bing

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