Editorial : : chemical allergy and the relevance of new models

Abstract: Chemical allergy represents an adverse health effect that results from an immune response activation following chemical exposure. Among the different forms of chemical allergies, the two most relevant for occupational toxicology are allergic contact dermatitis, and occupational rhinitis and asthma. Chemical allergens are low molecular weight molecules able to activate the immune system. To stimulate an immune response, chemical allergens function as haptens binding to carrier proteins. Several molecules can be involved in chemical allergy either as haptens or immune danger signals such as micro and nano-plastics, particles, pesticides, endocrine disruptors, drugs, fragrances, among others. The initiation and development of chemical allergy phenomena are of considerable interest and importance also for the toxicologist, who has the responsibility of identifying and characterizing the allergenic potential of chemicals and estimating the risk they pose to human health.

This Research Topic aimed to combine interdisciplinary evidence on chemical allergy, covering the biological, pharmaceutical, toxicological, and clinical points of view. The purpose was to evaluate experimental evidence supporting the contribution of these interactions in chemical allergy

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch
• Notes: Frontiers in toxicology. - 5 (2023) , 1228175, ISSN: 2673-3080

Contributors, Places and Time

• Event: Veröffentlichung
• (where): Freiburg
• (who): Universität
• (when): 2023
• Creator: Pallardy, Marc ; Galbiati, Valentina ; Martin, Stefan F.

Further information

• DOI: 10.3389/ftox.2023.1228175
• URN: urn:nbn:de:bsz:25-freidok-2379650
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 25.03.2025, 1:55 PM CET