Regiospecific N‐Arylation of Aliphatic Amines under Mild and Metal‐Free Reaction Conditions

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Abstract: A transition metal‐free N‐arylation of primary and secondary amines with diaryliodonium salts is presented. Both acyclic and cyclic amines are well tolerated, providing a large set of N‐alkyl anilines. The methodology is unprecedented among metal‐free methods in terms of amine scope, the ability to transfer both electron‐withdrawing and electron‐donating aryl groups, and efficient use of resources, as excess substrate or reagents are not required.

Location: Deutsche Nationalbibliothek Frankfurt am Main

Extent: Online-Ressource

Language: Englisch

Bibliographic citation: Regiospecific N‐Arylation of Aliphatic Amines under Mild and Metal‐Free Reaction Conditions ; volume:130 ; number:35 ; year:2018 ; pages:11597-11601 ; extent:5
Angewandte Chemie ; 130, Heft 35 (2018), 11597-11601 (gesamt 5)

Creator: Purkait, Nibadita
Kervefors, Gabriella
Linde, Erika
Olofsson, Berit

DOI: 10.1002/ange.201807001

URN: urn:nbn:de:101:1-2022082005584894916383

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 15.08.2025, 7:37 AM CEST

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Associated

Purkait, Nibadita
Kervefors, Gabriella
Linde, Erika
Olofsson, Berit

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