Room Temperature, Metal‐Free Arylation of Aliphatic Alcohols
Abstract: Diaryliodonium salts are demonstrated as efficient arylating agents of aliphatic alcohols under metal‐free conditions. The reaction proceeds at room temperature within 90 min to give alkyl aryl ethers in good to excellent yields. Aryl groups with electron‐withdrawing substituents are transferred most efficiently, and unsymmetric iodonium salts give chemoselective arylations. The methodology has been applied to the formal synthesis of butoxycaine.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Room Temperature, Metal‐Free Arylation of Aliphatic Alcohols ; volume:3 ; number:2 ; year:2014 ; pages:54-57 ; extent:4
ChemistryOpen ; 3, Heft 2 (2014), 54-57 (gesamt 4)
- Creator
- DOI
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10.1002/open.201402006
- URN
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urn:nbn:de:101:1-2023011208551116445510
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:25 AM CEST
Data provider
This object is provided by:
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Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Ghosh, Raju
- Lindstedt, Erik
- Jalalian, Nazli
- Olofsson, Berit
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