Toxic effects of formaldehyde and the protective effect of docosahexaenoic acid in Drosophila
Abstract: Formaldehyde (FA) is a commercially important chemical applied in industry and scientific research. However, FA has a distinct impact on learning and memory. Although the mechanisms of FA toxicity have been well studied, additional research is required to establish the mechanisms of neuroprotection in cases of FA exposure. Docosahexaenoic acid (DHA) is a polyunsaturated fatty acid with a variety of health benefits, including the enhancement of learning and memory. In this study, we investigated the neuroprotective effects of DHA in Drosophila melanogaster that had ingested FA. Our data suggested that DHA enhanced reproductive processes, leading to an increase in the number of eggs, larvae, and adults. Surprisingly, we found that DHA had a mild protective effect against FA-induced impairments in learning and memory.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Toxic effects of formaldehyde and the protective effect of docosahexaenoic acid in Drosophila ; volume:12 ; number:1 ; year:2021 ; pages:351-361 ; extent:11
Translational Neuroscience ; 12, Heft 1 (2021), 351-361 (gesamt 11)
- Creator
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Hua, Yanli
Ma, Chao
Huang, Shuyi
Wang, Ruomeng
Chen, Jian
Guo, Qing
Zhou, Jiaojiao
Zhu, Hemin
Li, Wenjie
- DOI
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10.1515/tnsci-2020-0186
- URN
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urn:nbn:de:101:1-2022082914453436317488
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:29 AM CEST
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Associated
- Hua, Yanli
- Ma, Chao
- Huang, Shuyi
- Wang, Ruomeng
- Chen, Jian
- Guo, Qing
- Zhou, Jiaojiao
- Zhu, Hemin
- Li, Wenjie
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