Multidisciplinary consensus guideline for the diagnosis and management of spontaneous intracranial hypotension

Abstract: Background We aimed to create a multidisciplinary consensus clinical guideline for best practice in the diagnosis, investigation and management of spontaneous intracranial hypotension (SIH) due to cerebrospinal fluid leak based on current evidence and consensus from a multidisciplinary specialist interest group (SIG).

Methods A 29-member SIG was established, with members from neurology, neuroradiology, anaesthetics, neurosurgery and patient representatives. The scope and purpose of the guideline were agreed by the SIG by consensus. The SIG then developed guideline statements for a series of question topics using a modified Delphi process. This process was supported by a systematic literature review, surveys of patients and healthcare professionals and review by several international experts on SIH.

Results SIH and its differential diagnoses should be considered in any patient presenting with orthostatic headache. First-line imaging should be MRI of the brain with contrast and the whole spine. First-line treatment is non-targeted epidural blood patch (EBP), which should be performed as early as possible. We provide criteria for performing myelography depending on the spine MRI result and response to EBP, and we outline principles of treatments. Recommendations for conservative management, symptomatic treatment of headache and management of complications of SIH are also provided.

Conclusions This multidisciplinary consensus clinical guideline has the potential to increase awareness of SIH among healthcare professionals, produce greater consistency in care, improve diagnostic accuracy, promote effective investigations and treatments and reduce disability attributable to SIH

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch
Notes
Journal of neurology, neurosurgery, and psychiatry. - 94, 10 (2023) , 835-843, ISSN: 1468-330X

Event
Veröffentlichung
(where)
Freiburg
(who)
Universität
(when)
2023
Creator
Cheema, Sanjay
Beck, Jürgen
Matharu, Manjit Singh

DOI
10.1136/jnnp-2023-331166
URN
urn:nbn:de:bsz:25-freidok-2368862
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
25.03.2025, 1:45 PM CET

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Associated

  • Cheema, Sanjay
  • Beck, Jürgen
  • Matharu, Manjit Singh
  • Universität

Time of origin

  • 2023

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