Use of donors at age extremes for simultaneous pancreas-kidney transplant
Introduction: There is a shortage of optimal pancreatic donors for simultaneous pancreas and kidney transplant (SPKT), as such there is interest in utilizing donors at extremes of age to expand the donor pool. We sought to evaluate outcomes in SPKT from pediatric donors (PDs) to older donors (ODs). Patients and Methods: We identified patients who underwent simultaneous pancreas and kidney transplant at a single, high-volume institution from 1988–2013. We evaluated for differences in transplant organ function (estimated glomerular filtration rate [GFR], serum glucose, and urine amylase), early (technical) graft loss, and patient and graft survival. Results: A total of 729 SPKT were performed during the study, with 32 PDs, 652 standard donors (SDs), and 45 ODs. Renal function was slightly worse in OD. Otherwise, graft function was similar between all three groups at up to 5 years. There was no difference in censored survival analyses for both kidney and pancreas allografts. There was comparable short-term and long-term patient survival among all groups. Conclusions: Overall, the use of pancreas from pediatric and ODs for SPKT has comparable outcome to SDs. Kidneys from donors above 50 may have lower GFR, but otherwise, have comparable long-term patient and graft survival.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Use of donors at age extremes for simultaneous pancreas-kidney transplant ; volume:10 ; number:04 ; year:2018 ; pages:108-114
Ibnosina journal of medicine and biomedical sciences ; 10, Heft 04 (2018), 108-114
- Contributor
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Akateh, Clifford
Elkhammas, Elmahdi
Pelletier, Ronald
Rajab, Amer
Henry, Mitchell
El-Hinnawi, Ashraf
- DOI
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10.4103/ijmbs.ijmbs_8_18
- URN
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urn:nbn:de:101:1-2022101003592125713856
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:35 AM CEST
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Associated
- Akateh, Clifford
- Elkhammas, Elmahdi
- Pelletier, Ronald
- Rajab, Amer
- Henry, Mitchell
- El-Hinnawi, Ashraf
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Different timing and risk factors of cause-specific pancreas graft loss after simultaneous pancreas kidney transplantation
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Influence of Intraoperative Hemodynamic Parameters on Outcome in Simultaneous Pancreas–Kidney Transplant Recipient
Intractable ascites associated with mycophenolate in a simultaneous kidney-pancreas transplant patient: a case report
Pancreas grafts for transplantation from donors with hypertension: an analysis of the scientific registry of transplant recipients database
Endovascular management of giant common iliac artery pseudoaneurysm after complications in simultaneous pancreas–kidney transplant: a case report
Pneumocystis jiroveci pneumonia in kidney and simultaneous pancreas kidney transplant recipients in the present era of routine post-transplant prophylaxis: risk factors and outcomes
Pancreas Transplantation from Donors after Circulatory Death: an Irrational Reluctance?
Single-balloon enteroscopy-guided hemostasis of an anastomotic ulcer in a patient with simultaneous enteric-drained pancreas–kidney transplant
Pre-operative ankle-brachial index for cardiovascular risk assessment in simultaneous pancreas–kidney transplant recipients: a simple and elegant strategy!
Different timing and risk factors of cause-specific pancreas graft loss after simultaneous pancreas kidney transplantation
Impact of pre-transplant dialysis modality on the outcome and health-related quality of life of patients after simultaneous pancreas-kidney transplantation
Cystatin and glomerular filtration rate equations in old renal transplant donors
Plasma proteome of brain-dead organ donors predicts heart-transplant outcome
Influence of Intraoperative Hemodynamic Parameters on Outcome in Simultaneous Pancreas–Kidney Transplant Recipient
Intractable ascites associated with mycophenolate in a simultaneous kidney-pancreas transplant patient: a case report
Pancreas grafts for transplantation from donors with hypertension: an analysis of the scientific registry of transplant recipients database
Endovascular management of giant common iliac artery pseudoaneurysm after complications in simultaneous pancreas–kidney transplant: a case report
Pneumocystis jiroveci pneumonia in kidney and simultaneous pancreas kidney transplant recipients in the present era of routine post-transplant prophylaxis: risk factors and outcomes
Pancreas Transplantation from Donors after Circulatory Death: an Irrational Reluctance?
Single-balloon enteroscopy-guided hemostasis of an anastomotic ulcer in a patient with simultaneous enteric-drained pancreas–kidney transplant
Pre-operative ankle-brachial index for cardiovascular risk assessment in simultaneous pancreas–kidney transplant recipients: a simple and elegant strategy!
Different timing and risk factors of cause-specific pancreas graft loss after simultaneous pancreas kidney transplantation
Impact of pre-transplant dialysis modality on the outcome and health-related quality of life of patients after simultaneous pancreas-kidney transplantation
Cystatin and glomerular filtration rate equations in old renal transplant donors