Executive dysfunction in treated phenylketonuric patients
Abstract: Objectives: Executive function deficits have been described in early and continuously treated patients with phenylketonuria (PKU). The aim of this study was to examine performance on executive function tasks of treated patients with PKU diagnosed by 2 years of age. Patients and methods: Ten patients with PKU and normal intelligence score who were diagnosed before the age of 2 years and subsequently treated continuously, were compared with 15 typically developing control children on a battery of neuropsychological tests, including the tower of London (TOL), continuous performance test (CPT), and Stroop test. Results: PKU cases showed significantly poorer performance on the TOL task compared to the control group with the difference being significant in the first three levels of the test. With the CPT, PKU cases had significantly more omission errors than control subjects. On the Stroop test there was no statistically significant difference between the groups. No significant correlati
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Anmerkungen
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Veröffentlichungsversion
begutachtet (peer reviewed)
In: European Child & Adolescent Psychiatry ; 18 (2009) 6 ; 360-368
- Ereignis
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Veröffentlichung
- (wo)
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Mannheim
- (wann)
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2009
- Urheber
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Azadi, Bahare
Seddigh, Arshia
Tehrani-Doost, Mehdi
Alaghband-Rad, Javad
Ashrafi, Mahmoud Reza
- DOI
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10.1007/s00787-009-0738-8
- URN
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urn:nbn:de:0168-ssoar-122830
- Rechteinformation
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Open Access unbekannt; Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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15.08.2025, 07:31 MESZ
Datenpartner
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Beteiligte
- Azadi, Bahare
- Seddigh, Arshia
- Tehrani-Doost, Mehdi
- Alaghband-Rad, Javad
- Ashrafi, Mahmoud Reza
Entstanden
- 2009
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Attention and executive functions in microsurgically treated patients after subarachnoid hemorrhage
Perinatal complications and executive dysfunction in early-onset schizophrenia
Theory of mind and executive dysfunction in chronic inflammatory demyelinating polyneuropathy
Privacy by design for an mHealth app addressing executive dysfunction
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Functional brain network mechanism of executive control dysfunction in temporal lobe epilepsy
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Baseline serum TSH levels predict the absence of thyroid dysfunction in cancer patients treated with immunotherapy
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