Value shapes the structure of schematic representations in the medial prefrontal cortex
Abstract: Adaptive cognition is fostered by knowledge about the structure and value of our environment. Here, we hypothesize that these two kinds of information are inherently intertwined as value-weighted schemas in the medial prefrontal cortex (mPFC). Schemas (e.g., of a social network) emerge by extracting commonalities across experiences and can be understood as graphs comprising nodes (e.g., people) and edges (e.g., their relationships). We sampled information about unique real-life environments (i.e., about personally familiar people and places) and probed the neural representations of their schemas with fMRI. Using representational similarity analysis, we show that the mPFC encodes indeed both, the nodes and edges of the schemas. Critically, as hypothesized, the strength of the edges is not only determined by experience and centrality of a node but also by value. We thus account for the involvement of the mPFC in disparate functions and suggest that valuation emerges naturally from encoded memory representations
- Location
-
Deutsche Nationalbibliothek Frankfurt am Main
- Extent
-
Online-Ressource
- Language
-
Englisch
- Event
-
Veröffentlichung
- (where)
-
Freiburg
- (who)
-
Universität
- (when)
-
2023
- Creator
- DOI
-
10.1101/2020.08.21.260950
- URN
-
urn:nbn:de:bsz:25-freidok-2339058
- Rights
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
-
25.03.2025, 1:56 PM CET
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Paulus, Philipp C.
- Charest, Ian
- Benoit, Roland G.
- Universität
Time of origin
- 2023
Other Objects (12)
Anxiety, inhibition and the prefrontal cortex
Stable numerosity representations irrespective of magnitude context in macaque prefrontal cortex
Stable numerosity representations irrespective of magnitude context in macaque prefrontal cortex
Theta oscillations coordinate grid-like representations between ventromedial prefrontal and entorhinal cortex
The functional organization of the human lateral prefrontal cortex
Epigenetic Dysregulation in the Prefrontal Cortex of Suicide Completers
Specifying the role of the ventromedial prefrontal cortex in memory formation
Rapid plasticity in the prefrontal cortex during affective associative learning
Medial prefrontal cortex stimulation modulates the processing of conditioned fear
Modulating the Fear Network: Preclinical Studies on Prefrontal Cortex Stimulation
Is the medial prefrontal cortex necessary for Theory of Mind?
Medial prefrontal cortex stimulation modulates the processing of conditioned fear
Anxiety, inhibition and the prefrontal cortex
Stable numerosity representations irrespective of magnitude context in macaque prefrontal cortex
Stable numerosity representations irrespective of magnitude context in macaque prefrontal cortex
Theta oscillations coordinate grid-like representations between ventromedial prefrontal and entorhinal cortex
The functional organization of the human lateral prefrontal cortex
Epigenetic Dysregulation in the Prefrontal Cortex of Suicide Completers
Specifying the role of the ventromedial prefrontal cortex in memory formation
Rapid plasticity in the prefrontal cortex during affective associative learning
Medial prefrontal cortex stimulation modulates the processing of conditioned fear
Modulating the Fear Network: Preclinical Studies on Prefrontal Cortex Stimulation
Is the medial prefrontal cortex necessary for Theory of Mind?
Medial prefrontal cortex stimulation modulates the processing of conditioned fear
Anxiety, inhibition and the prefrontal cortex
Stable numerosity representations irrespective of magnitude context in macaque prefrontal cortex
Stable numerosity representations irrespective of magnitude context in macaque prefrontal cortex
Theta oscillations coordinate grid-like representations between ventromedial prefrontal and entorhinal cortex
The functional organization of the human lateral prefrontal cortex
Epigenetic Dysregulation in the Prefrontal Cortex of Suicide Completers
Specifying the role of the ventromedial prefrontal cortex in memory formation
Rapid plasticity in the prefrontal cortex during affective associative learning
Medial prefrontal cortex stimulation modulates the processing of conditioned fear
Modulating the Fear Network: Preclinical Studies on Prefrontal Cortex Stimulation
Is the medial prefrontal cortex necessary for Theory of Mind?