Synthesis of H4 pantetheine adducts for histone acetyltransferase inhibition
Abstract: Site-specific modifications of peptides provide a powerful tool for design of chemical probes and enzyme inhibitors. A convenient synthesis method was developed and used to produce H4K16-pantetheine bisubstrate analogs which could be employed as inhibitors of histone acetyltransferases in vivo and in vitro.
- Location
-
Deutsche Nationalbibliothek Frankfurt am Main
- Extent
-
Online-Ressource
- Language
-
Englisch
- Bibliographic citation
-
Synthesis of H4 pantetheine adducts for histone acetyltransferase inhibition ; volume:16 ; number:4-6 ; year:2010 ; pages:231-234
Heterocyclic communications ; 16, Heft 4-6 (2010), 231-234
- Creator
-
Wu, Jiang
Zheng, Yujun George
- DOI
-
10.1515/HC.2010.014
- URN
-
urn:nbn:de:101:1-2501130541512.734231721710
- Rights
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
-
25.03.20252151, 4:08 PM CET
Data provider
This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Wu, Jiang
- Zheng, Yujun George
Other Objects (12)
Histone acetyltransferase PCAF Up-regulated cell apoptosis in hepatocellular carcinoma via acetylating histone H4 and inactivating AKT signaling
Correction: Histone acetyltransferase PCAF Up-regulated cell apoptosis in hepatocellular carcinoma via acetylating histone H4 and inactivating AKT signaling
The NuA4 acetyltransferase and histone H4 acetylation promote replication recovery after topoisomerase I-poisoning
Synthesis of Histone Acetyltransferase Inhibitor A-485
Genome protection: histone H4 and beyond
Inhibition of histone acetyltransferase (HAT) activity by HBZ extends beyond the p300/CBP HAT family
Histone acetyltransferase inhibitors block neuroblastoma cell growth in vivo
Chromatin regulation by the histone acetyltransferase MOF in Drosphila
The CSRP2BP histone acetyltransferase drives smooth muscle gene expression
UFL1 promotes histone H4 ufmylation and ATM activation
NuA4 histone acetyltransferase activity is required for H4 acetylation on a dosage-compensated monosomic chromosome that confers resistance to fungal toxins
Characterization of the MYST histone acetyltransferase Mof2 in Drosophila melanogaster
Histone acetyltransferase PCAF Up-regulated cell apoptosis in hepatocellular carcinoma via acetylating histone H4 and inactivating AKT signaling
Correction: Histone acetyltransferase PCAF Up-regulated cell apoptosis in hepatocellular carcinoma via acetylating histone H4 and inactivating AKT signaling
The NuA4 acetyltransferase and histone H4 acetylation promote replication recovery after topoisomerase I-poisoning
Synthesis of Histone Acetyltransferase Inhibitor A-485
Genome protection: histone H4 and beyond
Inhibition of histone acetyltransferase (HAT) activity by HBZ extends beyond the p300/CBP HAT family
Histone acetyltransferase inhibitors block neuroblastoma cell growth in vivo
Chromatin regulation by the histone acetyltransferase MOF in Drosphila
The CSRP2BP histone acetyltransferase drives smooth muscle gene expression
UFL1 promotes histone H4 ufmylation and ATM activation
NuA4 histone acetyltransferase activity is required for H4 acetylation on a dosage-compensated monosomic chromosome that confers resistance to fungal toxins
Characterization of the MYST histone acetyltransferase Mof2 in Drosophila melanogaster
Histone acetyltransferase PCAF Up-regulated cell apoptosis in hepatocellular carcinoma via acetylating histone H4 and inactivating AKT signaling
Correction: Histone acetyltransferase PCAF Up-regulated cell apoptosis in hepatocellular carcinoma via acetylating histone H4 and inactivating AKT signaling
The NuA4 acetyltransferase and histone H4 acetylation promote replication recovery after topoisomerase I-poisoning
Synthesis of Histone Acetyltransferase Inhibitor A-485
Genome protection: histone H4 and beyond
Inhibition of histone acetyltransferase (HAT) activity by HBZ extends beyond the p300/CBP HAT family
Histone acetyltransferase inhibitors block neuroblastoma cell growth in vivo
Chromatin regulation by the histone acetyltransferase MOF in Drosphila
The CSRP2BP histone acetyltransferase drives smooth muscle gene expression
UFL1 promotes histone H4 ufmylation and ATM activation
NuA4 histone acetyltransferase activity is required for H4 acetylation on a dosage-compensated monosomic chromosome that confers resistance to fungal toxins