Exploiting Nonlinear Fiber Patterning to Control Tubular Scaffold Mechanical Behavior
Abstract: Melt electrowriting is an additive manufacturing technique capable of fabricating highly biomimetic polymer scaffolds with high‐resolution microarchitecture for a range of tissue engineering applications. The use of a rotating mandrel to fabricate tubular scaffolds using this technique is increasing in popularity; however, the translation of many novel scaffold designs that have been explored on flat collectors has yet to be realized using mandrels. This study reports novel tools to automatically generate scaffold gcode for several new tubular scaffold designs, investigating a range of auxetic pore geometries and open unit cell designs. Through optimization of printing parameters, the novel scaffold designs are successfully printed and mechanically tested to assess tensile properties. Open unit cells significantly reduce the tensile stiffness of scaffolds manufactured with closed pores. Auxetic scaffolds could also be widely tuned using the novel gcode generator tool to exhibit similar stress–strain profiles to typical crosshatch scaffolds but could be made to expand to desired radial dimensions. Finally, heterogeneous auxetic constructs are also fabricated with regions of various radial compliances. This study presents several, mechanically validated novel scaffold designs that are of interest for future applications in targeted tissue engineering product development as well as in soft robotic actuation.
- Standort
-
Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
-
Online-Ressource
- Sprache
-
Englisch
- Erschienen in
-
Exploiting Nonlinear Fiber Patterning to Control Tubular Scaffold Mechanical Behavior ; day:13 ; month:07 ; year:2022 ; extent:8
Advanced Materials Technologies ; (13.07.2022) (gesamt 8)
- Urheber
-
McCosker, Audrey B.
Snowdon, Mikayla E.
Lamont, Riki
Woodruff, Maria A.
Paxton, Naomi C.
- DOI
-
10.1002/admt.202200259
- URN
-
urn:nbn:de:101:1-2022071415284509398401
- Rechteinformation
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
-
15.08.2025, 07:24 MESZ
Datenpartner
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- McCosker, Audrey B.
- Snowdon, Mikayla E.
- Lamont, Riki
- Woodruff, Maria A.
- Paxton, Naomi C.
Ähnliche Objekte (12)
Fiber Scaffold Patterning for Mending Hearts: 3D Organization Bringing the Next Step
Hybrid approaches to nanometer-scale patterning: Exploiting tailored intermolecular interactions
Additively manufactured 3D short carbon fiber scaffold for thermoset composites
A novel polymeric fibrous microstructured biodegradable small-caliber tubular scaffold for cardiovascular tissue engineering
Mechano-biological computer model of scaffold-supported bone regeneration : effect of bone graft and scaffold structure on large bone defect tissue patterning
The patterning toolbox FIB-o-mat: Exploiting the full potential of focused helium ions for nanofabrication
Bio-Inspired Fiber Reinforcement for Aortic Valves: Scaffold Production Process and Characterization
Scharfentrahmer Tubular
Tubular optofluidics
Biosoluble ceramic fiber reinforced poly(L-lactic acid) bone scaffold: degradation and bioactivity
Woven Carbon-Fiber-Reinforced Polymer Tubular Mesh Reinforcement of Hollow High-Performance Concrete Beams
Coiled-coil peptides as multivalent scaffold for carbohydrates: from receptor targeting to vaccine exploiting sugar-protein interactions
Fiber Scaffold Patterning for Mending Hearts: 3D Organization Bringing the Next Step
Hybrid approaches to nanometer-scale patterning: Exploiting tailored intermolecular interactions
Additively manufactured 3D short carbon fiber scaffold for thermoset composites
A novel polymeric fibrous microstructured biodegradable small-caliber tubular scaffold for cardiovascular tissue engineering
Mechano-biological computer model of scaffold-supported bone regeneration : effect of bone graft and scaffold structure on large bone defect tissue patterning
The patterning toolbox FIB-o-mat: Exploiting the full potential of focused helium ions for nanofabrication
Bio-Inspired Fiber Reinforcement for Aortic Valves: Scaffold Production Process and Characterization
Scharfentrahmer Tubular
Tubular optofluidics
Biosoluble ceramic fiber reinforced poly(L-lactic acid) bone scaffold: degradation and bioactivity
Woven Carbon-Fiber-Reinforced Polymer Tubular Mesh Reinforcement of Hollow High-Performance Concrete Beams
Coiled-coil peptides as multivalent scaffold for carbohydrates: from receptor targeting to vaccine exploiting sugar-protein interactions
Fiber Scaffold Patterning for Mending Hearts: 3D Organization Bringing the Next Step
Hybrid approaches to nanometer-scale patterning: Exploiting tailored intermolecular interactions
Additively manufactured 3D short carbon fiber scaffold for thermoset composites
A novel polymeric fibrous microstructured biodegradable small-caliber tubular scaffold for cardiovascular tissue engineering
Mechano-biological computer model of scaffold-supported bone regeneration : effect of bone graft and scaffold structure on large bone defect tissue patterning
The patterning toolbox FIB-o-mat: Exploiting the full potential of focused helium ions for nanofabrication
Bio-Inspired Fiber Reinforcement for Aortic Valves: Scaffold Production Process and Characterization
Scharfentrahmer Tubular
Tubular optofluidics
Biosoluble ceramic fiber reinforced poly(L-lactic acid) bone scaffold: degradation and bioactivity
Woven Carbon-Fiber-Reinforced Polymer Tubular Mesh Reinforcement of Hollow High-Performance Concrete Beams