Systematic morphological characterization of sub-visible particles generated from cardiovascular devices using dynamic image analysis
Abstract: The assessment of particulate matter generated during a simulated use is requested by international standards for approval of cardiovascular devices. The particle suspension was generated during a simulated use test procedure of a commercially available coronary stent delivery system and analyzed by Dynamic image analysis (DIA) using FlowCAM 8000. Four parameters were analyzed: the diameter, the aspect ratio value, the circularity and the intensity. The results revealed that 53% of the particles were larger than 25 μm. The particle shapes were inhomogeneous with a wide ranging aspect ratio of 0.03 to 0.95. Around 83% had an intensity value of more than 140 grey scales and appeared translucent.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Systematic morphological characterization of sub-visible particles generated from cardiovascular devices using dynamic image analysis ; volume:7 ; number:2 ; year:2021 ; pages:617-620 ; extent:4
Current directions in biomedical engineering ; 7, Heft 2 (2021), 617-620 (gesamt 4)
- Urheber
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Kurzhals, Anja
Brandt-Wunderlich, Christoph
Schmitz, Klaus-Peter
Grabow, Niels
Schmidt, Wolfram
- DOI
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10.1515/cdbme-2021-2157
- URN
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urn:nbn:de:101:1-2022101214153058207630
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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15.08.2025, 07:32 MESZ
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Beteiligte
- Kurzhals, Anja
- Brandt-Wunderlich, Christoph
- Schmitz, Klaus-Peter
- Grabow, Niels
- Schmidt, Wolfram
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