Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aβ generation in Alzheimer’s disease
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- ISSN
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1432-0533
- Extent
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Online-Ressource
- Language
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Englisch
- Notes
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online resource.
- Bibliographic citation
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Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aβ generation in Alzheimer’s disease ; day:18 ; month:3 ; year:2016 ; pages:1-22
Acta neuropathologica ; (18.3.2016), 1-22
- Creator
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Sadleir, Katherine R.
- Contributor
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Kandalepas, Patty C.
Buggia-Prévot, Virginie
Nicholson, Daniel A.
Thinakaran, Gopal
Vassar, Robert
SpringerLink (Online service)
- DOI
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10.1007/s00401-016-1558-9
- URN
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urn:nbn:de:1111-201603258394
- Rights
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Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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14.08.2025, 10:53 AM CEST
Data provider
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Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Sadleir, Katherine R.
- Kandalepas, Patty C.
- Buggia-Prévot, Virginie
- Nicholson, Daniel A.
- Thinakaran, Gopal
- Vassar, Robert
- SpringerLink (Online service)
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Role of BACE1 in Alzheimer’s synaptic function
Function and substrates of the Alzheimer´s disease protease BACE1
BACE1 inhibitor drugs in clinical trials for Alzheimer’s disease
The Alzheimer's disease β-secretase enzyme, BACE1
BACE1, the Alzheimer’s beta-secretase enzyme, in health and disease
Platelet BACE1 levels as a possible biomarker for Alzheimer’s disease
Stepping closer to treating Alzheimer’s disease patients with BACE1 inhibitor drugs
Dystrophic neurites express C9orf72 in Alzheimer's disease brains
Sequential formation of different layers of dystrophic neurites in Alzheimer’s brains
Sorting out the cell biology of Alzheimer’s disease: focus on BACE1 and APP
CSF levels of the BACE1 substrate NRG1 correlate with cognition in Alzheimer’s disease
The Alzheimer’s β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques
Role of BACE1 in Alzheimer’s synaptic function
Function and substrates of the Alzheimer´s disease protease BACE1
BACE1 inhibitor drugs in clinical trials for Alzheimer’s disease
The Alzheimer's disease β-secretase enzyme, BACE1
BACE1, the Alzheimer’s beta-secretase enzyme, in health and disease
Platelet BACE1 levels as a possible biomarker for Alzheimer’s disease
Stepping closer to treating Alzheimer’s disease patients with BACE1 inhibitor drugs
Dystrophic neurites express C9orf72 in Alzheimer's disease brains
Sequential formation of different layers of dystrophic neurites in Alzheimer’s brains
Sorting out the cell biology of Alzheimer’s disease: focus on BACE1 and APP