Acute Kidney Injury after Cardiac Surgery

Abstract: Background: Cardiac surgery-associated acute kidney injury (CS-AKI) remains a vexing issue. Clinical trials for the prevention of CS-AKI have been disappointing despite enormous initial enthusiasm based on experimental data. Summary: The schism in experimental and clinical data has triggered a relook at our understanding of CS-AKI and the experimental and preclinical models. In this review, we discuss the therapeutic targets of major clinical trials. Key Messages: The silver lining in the midst is the standardization of anesthetic and perioperative care proposed by national societies. Implementation of the KDIGO bundle is a reasonable option to decrease the incidence of CS-AKI despite lack of proven robust benefits.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Acute Kidney Injury after Cardiac Surgery ; volume:14 ; number:1 ; year:2024 ; pages:437-442 ; extent:6
Cardiorenal Medicine ; 14, Heft 1 (2024), 437-442 (gesamt 6)

Creator
Beaver, Thomas M.
Dass, Bhagwan
Patel, Ami M.
Ejaz, A. Ahsan

DOI
10.1159/000540396
URN
urn:nbn:de:101:1-2412260032480.321224167779
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:38 AM CEST

Data provider

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Associated

  • Beaver, Thomas M.
  • Dass, Bhagwan
  • Patel, Ami M.
  • Ejaz, A. Ahsan

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