Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species

to related objects

Location: Deutsche Nationalbibliothek Frankfurt am Main

ISSN: 1741-7007

Extent: Online-Ressource

Language: Englisch

Notes: online resource.

Bibliographic citation: Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species ; volume:15 ; number:1 ; day:3 ; month:7 ; year:2017 ; pages:1-14 ; date:12.2017
BMC biology ; 15, Heft 1 (3.7.2017), 1-14, 12.2017

Classification: Biowissenschaften, Biologie

Creator: Iljina, Marija

Contributor: Hong, Liu
Horrocks, Mathew H.
Ludtmann, Marthe H.
Choi, Minee L.
Hughes, Craig D.
Ruggeri, Francesco S.
Guilliams, Tim
Buell, Alexander K.
Lee, Ji-Eun
Gandhi, Sonia
Lee, Steven F.
Bryant, Clare E.
Vendruscolo, Michele
Knowles, Tuomas P. J.
Dobson, Christopher M.
De Genst, Erwin
Klenerman, David
SpringerLink (Online service)

DOI: 10.1186/s12915-017-0390-6

URN: urn:nbn:de:1111-201709255394

Rights: Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 15.08.2025, 7:20 AM CEST

Data provider

This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.

Show original at data provider

Associated

Iljina, Marija
Hong, Liu
Horrocks, Mathew H.
Ludtmann, Marthe H.
Choi, Minee L.
Hughes, Craig D.
Ruggeri, Francesco S.
Guilliams, Tim
Buell, Alexander K.
Lee, Ji-Eun
Gandhi, Sonia
Lee, Steven F.
Bryant, Clare E.
Vendruscolo, Michele
Knowles, Tuomas P. J.
Dobson, Christopher M.
De Genst, Erwin
Klenerman, David
SpringerLink (Online service)

Other Objects (12)

Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide

In Vitro Faecal Fermentation of Monomeric and Oligomeric Flavan‐3‐ols: Catabolic Pathways and Stoichiometry

Efficiency of Monomeric and Oligomeric Forms of Phenolic Acids Extracted from Wheat Durum Bran to Modulate TCTB Biosynthesis by Fusarium

Thermodynamic and conformational analysis of monomeric Aβ isoforms binding with Aβ(1-42) fibril - insights into the secondary nucleation of amyloidosis

Protofibril–Fibril Interactions Inhibit Amyloid Fibril Assembly by Obstructing Secondary Nucleation

Effects of oligomer toxicity, fibril toxicity and fibril spreading in synucleinopathies

The Therapeutic Potential of Nanobodies

Nanobodies – effektive Immunwaffen gegen Krebs

Diphosphetanes from monomeric alkylidene phosphines

Hochschulschrift

Modelling fibril formation on membrane surfaces

Physical basis of amyloid fibril polymorphism

A Photo‐Switchable Peptide Fibril Esterase

Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide

In Vitro Faecal Fermentation of Monomeric and Oligomeric Flavan‐3‐ols: Catabolic Pathways and Stoichiometry

Efficiency of Monomeric and Oligomeric Forms of Phenolic Acids Extracted from Wheat Durum Bran to Modulate TCTB Biosynthesis by Fusarium

Thermodynamic and conformational analysis of monomeric Aβ isoforms binding with Aβ(1-42) fibril - insights into the secondary nucleation of amyloidosis

Protofibril–Fibril Interactions Inhibit Amyloid Fibril Assembly by Obstructing Secondary Nucleation

Effects of oligomer toxicity, fibril toxicity and fibril spreading in synucleinopathies

The Therapeutic Potential of Nanobodies

Nanobodies – effektive Immunwaffen gegen Krebs

Diphosphetanes from monomeric alkylidene phosphines

Hochschulschrift

Modelling fibril formation on membrane surfaces

Physical basis of amyloid fibril polymorphism

A Photo‐Switchable Peptide Fibril Esterase

Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide

In Vitro Faecal Fermentation of Monomeric and Oligomeric Flavan‐3‐ols: Catabolic Pathways and Stoichiometry

Efficiency of Monomeric and Oligomeric Forms of Phenolic Acids Extracted from Wheat Durum Bran to Modulate TCTB Biosynthesis by Fusarium

Thermodynamic and conformational analysis of monomeric Aβ isoforms binding with Aβ(1-42) fibril - insights into the secondary nucleation of amyloidosis

Protofibril–Fibril Interactions Inhibit Amyloid Fibril Assembly by Obstructing Secondary Nucleation

Effects of oligomer toxicity, fibril toxicity and fibril spreading in synucleinopathies

The Therapeutic Potential of Nanobodies

Nanobodies – effektive Immunwaffen gegen Krebs

Diphosphetanes from monomeric alkylidene phosphines

Hochschulschrift

Modelling fibril formation on membrane surfaces

Physical basis of amyloid fibril polymorphism

A Photo‐Switchable Peptide Fibril Esterase

Cultural heritage institutions wishing to register will find more information here.

Fields marked * need to be filled in.

Username*

Please enter your username

Email*

Please enter your email address

Please do not fill this field

First name

Last name

Password*

Please enter your password

Confirm password*

Please enter the same password

I have read the terms of use and the privacy policy for the collection of personal data and accept them. *

This field is required.

I would like to subscribe to the newsletter of the Deutsche Digitale Bibliothek. See newsletter subscription info.

Account created

Your "My DDB" account has been successfully created. Before you can log in to your account, you must click the confirmation link in the message we just sent to the email address you provided.

Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species

Object Details

References and Relationships

Classification and Topics

Contributors, Places and Time

Further information

Data provider

Associated

Other Objects (12)

Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide

In Vitro Faecal Fermentation of Monomeric and Oligomeric Flavan‐3‐ols: Catabolic Pathways and Stoichiometry

Efficiency of Monomeric and Oligomeric Forms of Phenolic Acids Extracted from Wheat Durum Bran to Modulate TCTB Biosynthesis by Fusarium

Thermodynamic and conformational analysis of monomeric Aβ isoforms binding with Aβ(1-42) fibril - insights into the secondary nucleation of amyloidosis

Protofibril–Fibril Interactions Inhibit Amyloid Fibril Assembly by Obstructing Secondary Nucleation

Effects of oligomer toxicity, fibril toxicity and fibril spreading in synucleinopathies

The Therapeutic Potential of Nanobodies

Nanobodies – effektive Immunwaffen gegen Krebs

Diphosphetanes from monomeric alkylidene phosphines

Modelling fibril formation on membrane surfaces

Physical basis of amyloid fibril polymorphism

A Photo‐Switchable Peptide Fibril Esterase

Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide

In Vitro Faecal Fermentation of Monomeric and Oligomeric Flavan‐3‐ols: Catabolic Pathways and Stoichiometry

Efficiency of Monomeric and Oligomeric Forms of Phenolic Acids Extracted from Wheat Durum Bran to Modulate TCTB Biosynthesis by Fusarium

Thermodynamic and conformational analysis of monomeric Aβ isoforms binding with Aβ(1-42) fibril - insights into the secondary nucleation of amyloidosis

Protofibril–Fibril Interactions Inhibit Amyloid Fibril Assembly by Obstructing Secondary Nucleation

Effects of oligomer toxicity, fibril toxicity and fibril spreading in synucleinopathies

The Therapeutic Potential of Nanobodies

Nanobodies – effektive Immunwaffen gegen Krebs

Diphosphetanes from monomeric alkylidene phosphines

Modelling fibril formation on membrane surfaces

Physical basis of amyloid fibril polymorphism

A Photo‐Switchable Peptide Fibril Esterase

Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide

In Vitro Faecal Fermentation of Monomeric and Oligomeric Flavan‐3‐ols: Catabolic Pathways and Stoichiometry

Efficiency of Monomeric and Oligomeric Forms of Phenolic Acids Extracted from Wheat Durum Bran to Modulate TCTB Biosynthesis by Fusarium

Thermodynamic and conformational analysis of monomeric Aβ isoforms binding with Aβ(1-42) fibril - insights into the secondary nucleation of amyloidosis

Protofibril–Fibril Interactions Inhibit Amyloid Fibril Assembly by Obstructing Secondary Nucleation

Effects of oligomer toxicity, fibril toxicity and fibril spreading in synucleinopathies

The Therapeutic Potential of Nanobodies

Nanobodies – effektive Immunwaffen gegen Krebs

Diphosphetanes from monomeric alkylidene phosphines

Modelling fibril formation on membrane surfaces

Physical basis of amyloid fibril polymorphism

A Photo‐Switchable Peptide Fibril Esterase

Related objects

Reset password