Biomarkers in Traumatic Brain Injuries: Narrative Review

Abstract: Traumatic brain injury (TBI) is a multistep interaction of brain antigens, cytokine-mediated humeral, and cellular immune reactions. Because of the limitations of clinical and radiological evaluation in TBI, there has been a considerable advancement toward the need for developing biomarkers that can predict the severity of TBI. Blood-based brain biomarkers hold the potential to predict the absence of intracranial injury and thus decrease unnecessary brain computed tomographic scanning. Various biomarkers have been studied that detects neuronal, axonal, and blood–brain barrier integrity. Biomarkers are still under investigation and hold promise in the future evaluation of TBI patients. They can be used for grading as well as a prognostication of head injury.

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Biomarkers in Traumatic Brain Injuries: Narrative Review ; day:23 ; month:12 ; year:2022 ; The Indian journal of neurotrauma ; (23.12.2022)

Contributors, Places and Time

• Contributor: Pandey, Vishram ; Shukla, Dhaval ; Nirmal, Shubham ; Devi, Bhagavatula Indira ; Christopher, Rita

Further information

• DOI: 10.1055/s-0042-1759853
• URN: urn:nbn:de:101:1-2023020911113840836716
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 14.08.2025, 10:49 AM CEST