Epithelial downgrowth masquerading as granulomatous anterior and intermediate uveitis with histopathologic evidence of 5-FU treatment
Abstract: Purpose: Highlight an unusual case of epithelial downgrowth (EDG) masquerading as granulomatous anterior and intermediate uveitis with histopathologic evidence of 5-fluorouracil (5-FU) treatment.Case description: A 33-year-old man presented after multiple corneal surgeries and neodymium-doped yttrium aluminum garnet (Nd:YAG) capsulotomies with subacute angle closure, pain, light sensitivity, and decreased vision. Exam was notable for granulomatous keratic precipitates, an opacified lens capsule, and vitreous cell/haze. An anterior chamber paracentesis was sent for 16 s (pan-bacterial) and 28 s (pan-fungal) rRNA polymerase chain reaction testing, which returned negative. Diagnostic argon laser photocoagulation was performed on the iris and lens capsule, which blanched upon laser photocoagulation, and subsequent iris biopsy confirmed the presence of epithelial downgrowth (EDG). The patient was treated with multiple injections of 5-FU with repeat biopsy demonstrating both a reducti...
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Epithelial downgrowth masquerading as granulomatous anterior and intermediate uveitis with histopathologic evidence of 5-FU treatment ; volume:14 ; day:23 ; month:09 ; year:2024
GMS ophthalmology cases ; 14 (23.09.2024)
- Klassifikation
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Medizin, Gesundheit
- Urheber
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Froines, Colin P.
Lin, Alexander D.
Pakzad-Vaezi, Kaivon
Juric-Sekhar, Gordana
Latimer, Caitlin S.
Scherpelz, Kathryn P.
Keene, C. Dirk
Hanna, Eissa M.
Banitt, Michael R.
Gonzalez-Cuyar, Luis F.
- DOI
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10.3205/oc000245
- URN
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urn:nbn:de:0183-oc0002452
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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15.08.2025, 07:21 MESZ
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Beteiligte
- Froines, Colin P.
- Lin, Alexander D.
- Pakzad-Vaezi, Kaivon
- Juric-Sekhar, Gordana
- Latimer, Caitlin S.
- Scherpelz, Kathryn P.
- Keene, C. Dirk
- Hanna, Eissa M.
- Banitt, Michael R.
- Gonzalez-Cuyar, Luis F.