The anti-catabolic role of bovine lactoferricin in cartilage

Abstract: Bovine lactoferricin (LfcinB) is a multifunctional peptide derived from bovine lactoferrin that demonstrates antibacterial, antifungal, antiviral, antitumor, and immunomodulatory activities. Recently, studies have focused on the anti-catabolic and anti-inflammatory potential of LfcinB. LfcinB is able to modulate the effects cytokines such as IL-1 and fibroblast growth factor 2 as well as promote specific cartilage anabolic factors. These properties are particularly important in maintaining cartilage homeostasis and preventing a catabolic state, which leads to clinical pathology. This review focuses on the recent literature elucidating the role of LfcinB in preventing cartilage degradation.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
The anti-catabolic role of bovine lactoferricin in cartilage ; volume:4 ; number:5 ; year:2013 ; pages:495-500
Biomolecular concepts ; 4, Heft 5 (2013), 495-500

Creator
Ahmadinia, Kasra
Yan, Dongyao
Ellman, Michael
Im, Hee-Jeong

DOI
10.1515/bmc-2013-0013
URN
urn:nbn:de:101:1-2409241615109.784787184131
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:39 AM CEST

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Associated

  • Ahmadinia, Kasra
  • Yan, Dongyao
  • Ellman, Michael
  • Im, Hee-Jeong

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