Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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1 Online-Ressource.
- Language
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Englisch
- Bibliographic citation
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Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis ; volume:41 ; number:11 ; day:23 ; month:2 ; year:2023 ; pages:1567-1581 ; date:11.2023
Nature biotechnology ; 41, Heft 11 (23.2.2023), 1567-1581, 11.2023
- Creator
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Hendriks, Delilah
Brouwers, Jos F.
Hamer, Karien
Geurts, Maarten H.
Luciana, Léa
Massalini, Simone
López-Iglesias, Carmen
Peters, Peter J.
Rodríguez-Colman, Maria J.
Chuva de Sousa Lopes, Susana
Artegiani, Benedetta
Clevers, Hans
- Contributor
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SpringerLink (Online service)
- DOI
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10.1038/s41587-023-01680-4
- URN
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urn:nbn:de:101:1-2024012910225208781559
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:20 AM CEST
Data provider
This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Hendriks, Delilah
- Brouwers, Jos F.
- Hamer, Karien
- Geurts, Maarten H.
- Luciana, Léa
- Massalini, Simone
- López-Iglesias, Carmen
- Peters, Peter J.
- Rodríguez-Colman, Maria J.
- Chuva de Sousa Lopes, Susana
- Artegiani, Benedetta
- Clevers, Hans
- SpringerLink (Online service)
Other Objects (12)
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Multiple MicroRNAs Ameliorate Hepatocyte Steatosis and Injury by Suppressing FABP1 Expression
Engineered Matrices Enable the Culture of Human Patient‐Derived Intestinal Organoids
Efficient hepatocyte differentiation of primary human hepatocyte-derived organoids using three dimensional nanofibers (HYDROX) and their possible application in hepatotoxicity research
Engineered Human Induced Pluripotent Cells Enable Genetic Code Expansion in Brain Organoids
Mapping of mitogen and metabolic sensitivity in organoids defines requirements for human hepatocyte growth
Decoding γδ T cell anticancer therapies: integrating CRISPR screens with tumor organoids
In-organoid single-cell CRISPR screening reveals determinants of hepatocyte differentiation and maturation
Hepatocyte high-mobility group box 1 protects against steatosis and cellular stress during high fat diet feeding
Alterations in the hepatocyte epigenetic landscape in steatosis
Hepatic stellate cells secrete Ccl5 to induce hepatocyte steatosis
Human primary epidermal organoids enable modeling of dermatophyte infections
Focused scores enable reliable discrimination of small differences in steatosis
Multiple MicroRNAs Ameliorate Hepatocyte Steatosis and Injury by Suppressing FABP1 Expression
Engineered Matrices Enable the Culture of Human Patient‐Derived Intestinal Organoids
Efficient hepatocyte differentiation of primary human hepatocyte-derived organoids using three dimensional nanofibers (HYDROX) and their possible application in hepatotoxicity research
Engineered Human Induced Pluripotent Cells Enable Genetic Code Expansion in Brain Organoids
Mapping of mitogen and metabolic sensitivity in organoids defines requirements for human hepatocyte growth
Decoding γδ T cell anticancer therapies: integrating CRISPR screens with tumor organoids
In-organoid single-cell CRISPR screening reveals determinants of hepatocyte differentiation and maturation
Hepatocyte high-mobility group box 1 protects against steatosis and cellular stress during high fat diet feeding
Alterations in the hepatocyte epigenetic landscape in steatosis
Hepatic stellate cells secrete Ccl5 to induce hepatocyte steatosis
Human primary epidermal organoids enable modeling of dermatophyte infections
Focused scores enable reliable discrimination of small differences in steatosis
Multiple MicroRNAs Ameliorate Hepatocyte Steatosis and Injury by Suppressing FABP1 Expression
Engineered Matrices Enable the Culture of Human Patient‐Derived Intestinal Organoids
Efficient hepatocyte differentiation of primary human hepatocyte-derived organoids using three dimensional nanofibers (HYDROX) and their possible application in hepatotoxicity research
Engineered Human Induced Pluripotent Cells Enable Genetic Code Expansion in Brain Organoids
Mapping of mitogen and metabolic sensitivity in organoids defines requirements for human hepatocyte growth
Decoding γδ T cell anticancer therapies: integrating CRISPR screens with tumor organoids
In-organoid single-cell CRISPR screening reveals determinants of hepatocyte differentiation and maturation