Hochschulschrift
Biomimetic layers of extracellular matrix glycoproteins as designed biointerfaces
Zusammenfassung: The goal of regenerative medicine is to guide biological systems towards natural healing outcomes using a combination of niche-specific cells, bioactive molecules and biomaterials. In this regard, mimicking the extracellular matrix (ECM) surrounding cells and tissues in vivo is an effective strategy to modulate cell behaviors. Cellular function and phenotype is directed by the biochemical and biophysical signals present in the complex 3D network of ECMs composed mainly of glycoproteins and hydrophilic proteoglycans. While cellular modulation in response to biophysical cues emulating ECM features has been investigated widely, the influence of biochemical display of ECM glycoproteins mimicking their presentation in vivo is not well characterized. It remains a significant challenge to build artificial biointerfaces using ECM glycoproteins that precisely match their presentation in nature in terms of morphology, orientation and conformation. This challenge becomes clear, when one understands how ECM glycoproteins self-assemble in the body. [...].
- Standort
-
Deutsche Nationalbibliothek Frankfurt am Main
- Maße
-
30 cm
- Umfang
-
1 Band (verschiedene Seitenzählungen)
- Sprache
-
Englisch
- Anmerkungen
-
Illustrationen, Diagramme
Kumulative Dissertation
Universität Potsdam, Dissertation, 2021
- Klassifikation
-
Biowissenschaften, Biologie
Medizin, Gesundheit
- Ereignis
-
Veröffentlichung
- (wo)
-
Potsdam
- (wann)
-
[2021?]
- Urheber
- Beteiligte Personen und Organisationen
- Inhaltsverzeichnis
- Rechteinformation
-
Bei diesem Objekt liegt nur das Inhaltsverzeichnis digital vor. Der Zugriff darauf ist unbeschränkt möglich.
- Letzte Aktualisierung
-
11.06.2025, 14:15 MESZ
Datenpartner
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Objekttyp
- Hochschulschrift
Beteiligte
Entstanden
- [2021?]
Ähnliche Objekte (12)
Involvement of extracellular glycoproteins in neuronal plasticity
Glycoproteins: Properties
Glycoproteins: Properties
Glycoproteins of the extracellular matrix mediate plasticity in the central nervous system
3D printable biomimetic rod with superior buckling resistance designed by machine learning
Nanoparticle‐Decorated Biomimetic Extracellular Matrix for Cell Nanoencapsulation and Regulation
Nanoparticle‐Decorated Biomimetic Extracellular Matrix for Cell Nanoencapsulation and Regulation
Glycoproteins: Occurrence and Significance
Metabolic Engineering of Glycoproteins
Material engineering and application of hybrid biomimetic-de novo designed elastin-like polypeptides
Rationally designed HIV envelope glycoproteins delivered in a novel adjuvant elicited more broadly reactive antigen-specific antibody responses
Nanofibrous polypeptide hydrogels with collagen-like structure as biomimetic extracellular matrix
Involvement of extracellular glycoproteins in neuronal plasticity
Glycoproteins: Properties
Glycoproteins: Properties
Glycoproteins of the extracellular matrix mediate plasticity in the central nervous system
3D printable biomimetic rod with superior buckling resistance designed by machine learning
Nanoparticle‐Decorated Biomimetic Extracellular Matrix for Cell Nanoencapsulation and Regulation
Nanoparticle‐Decorated Biomimetic Extracellular Matrix for Cell Nanoencapsulation and Regulation
Glycoproteins: Occurrence and Significance
Metabolic Engineering of Glycoproteins
Material engineering and application of hybrid biomimetic-de novo designed elastin-like polypeptides
Rationally designed HIV envelope glycoproteins delivered in a novel adjuvant elicited more broadly reactive antigen-specific antibody responses
Nanofibrous polypeptide hydrogels with collagen-like structure as biomimetic extracellular matrix
Involvement of extracellular glycoproteins in neuronal plasticity
Glycoproteins: Properties
Glycoproteins: Properties
Glycoproteins of the extracellular matrix mediate plasticity in the central nervous system
3D printable biomimetic rod with superior buckling resistance designed by machine learning
Nanoparticle‐Decorated Biomimetic Extracellular Matrix for Cell Nanoencapsulation and Regulation
Nanoparticle‐Decorated Biomimetic Extracellular Matrix for Cell Nanoencapsulation and Regulation
Glycoproteins: Occurrence and Significance
Metabolic Engineering of Glycoproteins
Material engineering and application of hybrid biomimetic-de novo designed elastin-like polypeptides
Rationally designed HIV envelope glycoproteins delivered in a novel adjuvant elicited more broadly reactive antigen-specific antibody responses