Neurodevelopmental disorders: 2023 update

Abstract: Several advances in the field of neurodevelopmental diseases (NDDs) have been reported by 2022. Of course, NDDs comprise a diverse group of disorders, most of which with different aetiologies. However, owing to the development and consolidation of technological approaches, such as proteomics and RNA-sequencing, and to the improvement of brain organoids along with the introduction of artificial intelligence (AI) for biodata analysis, in 2022 new aetiological mechanisms for some NDDs have been proposed. Here, we present hints of some of these findings. For instance, centrioles regulate neuronal migration and could be behind the aetiology of periventricular heterotopia; also, the accumulation of misfolded proteins could explain the neurological effects in COVID-19 patients; and, autism spectrum disorders (ASD) could be the expression of altered cortical arealization. We also cover other interesting aspects as the description of a new NDD characterized by deregulation of genes involved.... https://www.uni-muenster.de/Ejournals/index.php/fnp/article/view/4701

Angaben zum Objekt

• Standort: Deutsche Nationalbibliothek Frankfurt am Main
• Umfang: Online-Ressource
• Sprache: Englisch

Verweise und Beziehungen

• Erschienen in: Neurodevelopmental disorders: 2023 update ; volume:4 ; year:2023 ; Free Neuropathology ; 4 (2023)

Beteiligte, Orts- und Zeitangaben

• Urheber: Carriba, Paulina ; Lorenzón, Nicola ; Dierssen, Mara

Weitere Informationen

• DOI: 10.17879/freeneuropathology-2023-4701
• URN: urn:nbn:de:hbz:6:3-freeneuropathology-2023-49028
• Rechteinformation: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Letzte Aktualisierung: 14.01.2025, 20:51 MEZ