Primary Bilateral Ovarian Lymphoma: A Rare Case Report

Abstract: Primary ovarian lymphomas constitute 0.5% of all ovarian malignancies. We report one such case in a middle-aged woman who presented with a bilateral ovarian tumor. Bilateral oophorectomy with salpingectomy was sent for frozen section analysis that revealed a round cell tumor. Final histopathology showed a mitotically active small round blue cell tumor arranged in diffuse sheets and chords with an evident starry-sky pattern. Extensive immunohistochemistry (IHC) panel was performed. Histopathology along with IHC did not classify the tumor into diffuse-large-B cell-lymphoma or Burkitt lymphoma and a final diagnosis of high-grade B cell lymphoma (HGBL) was made. This case is presented for its rarity and to discuss the challenges on IHC to subclassify a lymphoma as HGBL. Although rare, the possibility of primary ovarian non-Hodgkin lymphoma should be kept in mind when dealing with bilateral ovarian tumors as a timely and accurate diagnosis can save unnecessary surgeries and improve outcome.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Primary Bilateral Ovarian Lymphoma: A Rare Case Report ; day:25 ; month:07 ; year:2022
Asian Journal of Oncology ; (25.07.2022)

Contributor
Bano, Salwa
Ramaswamy, Veena
Chandrashekar, Chaitra

DOI
10.1055/s-0042-1753497
URN
urn:nbn:de:101:1-2022092409042795114666
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:28 AM CEST

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Associated

  • Bano, Salwa
  • Ramaswamy, Veena
  • Chandrashekar, Chaitra

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