Sleep, Melatonin, and the Menopausal Transition: What Are the Links?

Abstract: The pineal hormone Melatonin plays an important role in the regulation of the circadian sleep/wake cycle, mood, and perhaps immune functions, carcinogensis and reproduction. The human circadian rhythm of melatonin release from the pineal gland is tightly synchronized with the habitual hours of sleep. Peri- and postmenopausal women often complain of difficulties initiating and/or maintaining sleep, with frequent nocturnal and early morning awakenings. In this review we discuss the pathophysiology of melatonin function as it relates to sleep disorders in menopausal women, highlighting the potential use of exogenous melatonin during the menopausal transition and beyond.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Sleep, Melatonin, and the Menopausal Transition: What Are the Links? ; volume:10 ; number:01 ; year:2017 ; pages:11-18
Sleep science ; 10, Heft 01 (2017), 11-18

Contributor
Jehan, Shazia
Jean-Louis, Giardin
Zizi, Ferdinand
Auguste, Evan
Pandi-Perumal, Seitikurippu R.
Gupta, Ravi
Attarian, Hrayr
McFarlane, Samy I.
Hardeland, Rüdiger
Brzezinski, Amnon

DOI
10.5935/1984-0063.20170003
URN
urn:nbn:de:101:1-2023113013595867459332
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:33 AM CEST

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Associated

  • Jehan, Shazia
  • Jean-Louis, Giardin
  • Zizi, Ferdinand
  • Auguste, Evan
  • Pandi-Perumal, Seitikurippu R.
  • Gupta, Ravi
  • Attarian, Hrayr
  • McFarlane, Samy I.
  • Hardeland, Rüdiger
  • Brzezinski, Amnon

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