Protein–Polymer Conjugates: Advancing Enzyme Catalysis in Synthetic Chemistry

Abstract: Enzyme catalysis is prominent in chemical synthesis due to its specificity, selectivity, and efficiency. However, enzymes often face challenges, such as inactivation and inhibition in practical applications, and they are also limited by narrow reaction scopes in complex catalytic scenarios like cascade reactions. These persistent issues have driven the development of chemical modifications of enzymes, aiming to enhance enzyme catalysis with external chemical entities. Polymers are particularly notable among these entities for their functional moieties and protective effects on biomolecules, enhancing enzyme properties, and even creating new‐to‐nature catalysis by harnessing catalytic promiscuity. This concept aims to introduce the field of protein–polymer conjugates for diverse emerging applications across emulsion biocatalysis, artificial enzymes, and supramolecular enzyme catalysis.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Protein–Polymer Conjugates: Advancing Enzyme Catalysis in Synthetic Chemistry ; day:08 ; month:10 ; year:2024 ; extent:9
ChemCatChem ; (08.10.2024) (gesamt 9)

Creator
Ouyang, Jingping
Li, Jian
Wu, Changzhu

DOI
10.1002/cctc.202401180
URN
urn:nbn:de:101:1-2410091409238.754849293674
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:26 AM CEST

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