Visible‐Light‐Mediated Decarboxylative Radical Additions to Vinyl Boronic Esters: Rapid Access to γ‐Amino Boronic Esters
Abstract: The synthesis of alkyl boronic esters by direct decarboxylative radical addition of carboxylic acids to vinyl boronic esters is described. The reaction proceeds under mild photoredox catalysis and involves an unprecedented single‐electron reduction of an α‐boryl radical intermediate to the corresponding anion. The reaction is amenable to a diverse range of substrates, including α‐amino, α‐oxy, and alkyl carboxylic acids, thus providing a novel method to rapidly access boron‐containing molecules of potential biological importance.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Visible‐Light‐Mediated Decarboxylative Radical Additions to Vinyl Boronic Esters: Rapid Access to γ‐Amino Boronic Esters ; volume:130 ; number:8 ; year:2018 ; pages:2177-2181 ; extent:5
Angewandte Chemie ; 130, Heft 8 (2018), 2177-2181 (gesamt 5)
- Urheber
- DOI
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10.1002/ange.201712186
- URN
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urn:nbn:de:101:1-2022090307451733011757
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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15.08.2025, 07:21 MESZ
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Beteiligte
- Noble, Adam
- Mega, Riccardo
- Pflästerer, Daniel
- Myers, Eddie L.
- Aggarwal, Varinder K.
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Ni-Catalyzed Alkyne Cycloaddition to Give Boronic Esters
Stereodivergent Olefination of Enantioenriched Boronic Esters
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Photoredox‐Mediated Deoxygenative Radical Additions of Aromatic Acids to Vinyl Boronic Esters and gem ‐Diborylalkenes **
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