Rotlicht-gesteuerter viraler Gentransfer mit Einzelzellauflösung

Abstract: Available methods for efficient gene transfer into user-selected or even single cells suffer from high invasiveness or the need for complicated equipment. Here, we present a technology for the light-guided transduction of native cell lines and primary cells by adeno-associated viral (AAV) vectors. We demonstrate the spatially resolved transduction of different cells with different genes within one culture and the selective transduction of single cells by local illumination

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Deutsch
Notes
BIOspektrum. - 27, 6 (2021) , 620-622, ISSN: 1868-6249

Keyword
Gentransfer
Zelle
Transduktion
Zelluläre Auflösung

Event
Veröffentlichung
(where)
Freiburg
(who)
Universität
(when)
2021
Creator

DOI
10.1007/s12268-021-1643-z
URN
urn:nbn:de:bsz:25-freidok-2224545
Rights
Kein Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:35 AM CEST

Data provider

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Associated

Time of origin

  • 2021

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