Single-session bilateral reduced-settings photodynamic therapy for bilateral chronic central serous chorioretinopathy
Abstract: Purpose:
We performed a multicenter, retrospective study on patients with bilateral chronic central serous chorioretinopathy (cCSC) who received single-session bilateral reduced-settings photodynamic therapy (ssbPDT) and assessed anatomical (resolution of subretinal fluid [SRF]) and functional (best-corrected visual acuity [BCVA]) outcomes and safety.
Methods:
Patients who underwent ssbPDT between 01/01/2011 and 30/09/2022 were included. The resolution of SRF at first, second, and final follow-up was assessed on optical coherence tomography (OCT), and BCVA measurements were collected at these visits. When fovea-involving ssbPDT was performed, ellipsoid zone (EZ) and external limiting membrane (ELM) integrity was graded before and after treatment.
Results:
Fifty-five patients were included in this study. Sixty-two of hundred and eight eyes (56%) showed a complete resolution of SRF at the first follow-up, which increased to 73/110 (66%) at the final follow-up. The mean logMAR BCVA improved by −0.047 (P = 0.02) over follow-up. EZ integrity increased from 14/21 (67%) to 24/30 (80%) while ELM integrity increased from 22/30 (73%) to 29/30 (97%).
Conclusion:
Patients with cCSC with bilateral SRF at baseline showed significant anatomical and functional improvements after ssbPDT, both at short-term and long-term follow-up. No relevant adverse events were noted
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Anmerkungen
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Retina. - 43, 8 (2023) , 1356-1363, ISSN: 0275-004X
- Ereignis
-
Veröffentlichung
- (wo)
-
Freiburg
- (wer)
-
Universität
- (wann)
-
2023
- Urheber
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Pauleikhoff, Laurenz
Diederen, Roselie M. H.
Feenstra, Helena
Schlingemann, Reinier O.
Dijk, Elon H.C. van
Boon, Camiel J.F.
- DOI
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10.1097/iae.0000000000003807
- URN
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urn:nbn:de:bsz:25-freidok-2372858
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
-
14.08.2025, 10:46 MESZ
Datenpartner
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Pauleikhoff, Laurenz
- Diederen, Roselie M. H.
- Feenstra, Helena
- Schlingemann, Reinier O.
- Dijk, Elon H.C. van
- Boon, Camiel J.F.
- Universität
Entstanden
- 2023
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