Autologous liver transplantation for unresectable hepatobiliary malignancies in enhanced recovery after surgery model

Abstract: Ex vivo liver resection combined with autologous liver transplantation offers the opportunity to treat otherwise unresectable hepatobiliary malignancies and has been applied in clinic. The implementation of enhanced recovery after surgery (ERAS) program improves the outcome of surgical procedures. This is a retrospective single-center study including 11 cases of patients with liver cancer that underwent autologous liver transplantation and received ERAS: cholangiocarcinoma of the hilar region (n = 5), intrahepatic cholangiocarcinoma (n = 3), gallbladder cancer (n = 1), liver metastasis from colorectal cancer (n = 1), and liver metastasis from gastrointestinal mesenchymal tumor (n = 1). There were no deaths within 30 days and major complications occurred in two patients, and four patients were readmitted upon the first month after the surgery. Median hospital stay was 20 days (range 13–44) and median open diet was Day 4 (range 2–9) after surgery and median early post-operative activity was Day 5 (range 2–9) after surgery. In conclusion, autologous liver transplantation is feasible in the treatment of otherwise unresectable hepatobiliary malignancies, and our study showed favorable results with autologous liver transplantation in ERAS modality. ERAS modality provides a good option for some patients whose tumors cannot be resected in situ and offers a chance for rapid recovery.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Autologous liver transplantation for unresectable hepatobiliary malignancies in enhanced recovery after surgery model ; volume:19 ; number:1 ; year:2024 ; extent:7
Open medicine ; 19, Heft 1 (2024) (gesamt 7)

Urheber
Liu, Weifeng
Li, Guogang
Jin, Yitian
Feng, Yihui
Gao, Zhenzhen
Liu, Xingyu
Zhou, Bo
Zheng, Xiang
Pei, Xiangru
Ying, Yulian
Yu, Qian
Yan, Sheng
Hu, Chenlu

DOI
10.1515/med-2024-0926
URN
urn:nbn:de:101:1-2024040115351831460280
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
14.08.2025, 10:44 MESZ

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Beteiligte

  • Liu, Weifeng
  • Li, Guogang
  • Jin, Yitian
  • Feng, Yihui
  • Gao, Zhenzhen
  • Liu, Xingyu
  • Zhou, Bo
  • Zheng, Xiang
  • Pei, Xiangru
  • Ying, Yulian
  • Yu, Qian
  • Yan, Sheng
  • Hu, Chenlu

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