Anti-D-induced severe hemolytic disease of the newborn in an Omani newborn born a rhesus-positive mother
Abstract: Hemolytic disease of the fetus and newborn (HDFN) due to anti-D antibodies is a well-known complication of rhesus (Rh) incompatibility, encountered in D-positive babies born to alloimmunized D-negative mothers who have been sensitized during previous labor or abortion. Here, we report a case of significant hemolytic disease of the newborn due to the presence of anti-D antibodies in an Rh-positive baby born to an Rh-positive mother. The boy presented at day 1 of life with neonatal jaundice and required intensive phototherapy. His hemoglobin (Hb) concentration gradually dropped from 17 g/dL to 6.6 g/dL. The blood bank workup revealed O Rh-positive blood group, with a positive direct antiglobulin test (DAT) and confirmed the presence of anti-D antibodies. His mother was typed as O Rh positive, with a negative DAT and positive anti-D. He required two blood transfusions, and his Hb stabilized at the age of 7 weeks. Anti-D HDFN is a rare complication of Rh-positive and Rh-weak positive pregnancies. The lack of awareness of this phenomenon is often a source of confusion for clinicians. A literature review of similar cases and possible explanations are discussed.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Anti-D-induced severe hemolytic disease of the newborn in an Omani newborn born a rhesus-positive mother ; volume:7 ; number:1 ; year:2018 ; extent:4
Case reports in perinatal medicine ; 7, Heft 1 (2018) (gesamt 4)
- Creator
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Nazir, Hanan F.
Al Harrasi, Huda
Al Hosni, Saif
Al Rawas, Abdulhakeem
Al-Riyami, Arwa
Fawaz, Naglaa
- DOI
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10.1515/crpm-2017-0047
- URN
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urn:nbn:de:101:1-2411121529364.091742218747
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:22 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Nazir, Hanan F.
- Al Harrasi, Huda
- Al Hosni, Saif
- Al Rawas, Abdulhakeem
- Al-Riyami, Arwa
- Fawaz, Naglaa
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