Lifetime Trauma History and Cognitive Functioning in Major Depression and Their Role for Cognitive-Behavioral Therapy Outcome

Abstract: Background: While cognitive-behavioral therapy (CBT) is the gold-standard psychological treatment for major depression (MD), non-response and lacking stability of treatment gains are persistent issues. Potential factors influencing treatment outcome might be lifetime trauma history and possibly associated primarily prefrontal-cortex- and hippocampus-dependent cognitive alterations. Method: We investigated MD and healthy control participants with (MD+T+, n = 37; MD-T+, n = 39) and without lifetime trauma history (MD+T-, n = 26; MD-T-, n = 45) regarding working memory, interference susceptibility, conflict adaptation, and autobiographical memory specificity. Further, MD+T+ (n = 21) and MD+T- groups (n = 16) were re-examined after 25 CBT sessions, with MD-T- individuals (n = 34) invited in parallel in order to explore the stability of cognitive alterations and the predictive value of lifetime trauma history, cognitive functioning, and their interaction for treatment outcome. Results: .... https://cpe.psychopen.eu/index.php/cpe/article/view/4105

Angaben zum Objekt

• Standort: Deutsche Nationalbibliothek Frankfurt am Main
• Umfang: Online-Ressource
• Sprache: Englisch

Verweise und Beziehungen

• Erschienen in: Lifetime Trauma History and Cognitive Functioning in Major Depression and Their Role for Cognitive-Behavioral Therapy Outcome ; volume:3 ; number:3 ; day:30 ; month:09 ; year:2021 ; Clinical psychology in Europe ; 3, Heft 3 (30.09.2021)

Beteiligte, Orts- und Zeitangaben

• Urheber: Schindler, Lena ; Stalder, Tobias ; Kirschbaum, Clemens ; Plessow, Franziska ; Schönfeld, Sabine ; Hoyer, Jürgen ; Trautmann, Sebastian ; Weidner, Kerstin ; Steudte-Schmiedgen, Susann

Weitere Informationen

• DOI: 10.32872/cpe.4105
• URN: urn:nbn:de:101:1-2021101605130934217950
• Rechteinformation: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Letzte Aktualisierung: 15.08.2025, 07:25 MESZ