Nucleo-cytoplasmic transport of TDP-43 studied in real time: impaired microglia function leads to axonal spreading of TDP-43 in degenerating motor neurons

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Location: Deutsche Nationalbibliothek Frankfurt am Main

ISSN: 1432-0533

Extent: Online-Ressource

Language: Englisch

Notes: online resource.

Bibliographic citation: Nucleo-cytoplasmic transport of TDP-43 studied in real time: impaired microglia function leads to axonal spreading of TDP-43 in degenerating motor neurons ; volume:136 ; number:3 ; day:25 ; month:6 ; year:2018 ; pages:445-459 ; date:9.2018
Acta neuropathologica ; 136, Heft 3 (25.6.2018), 445-459, 9.2018

Creator: Svahn, Adam J.

Contributor: Don, Emily K.
Badrock, Andrew P.
Cole, Nicholas J.
Graeber, Manuel B.
Yerbury, Justin J.
Chung, Roger
Morsch, Marco
SpringerLink (Online service)

DOI: 10.1007/s00401-018-1875-2

URN: urn:nbn:de:101:1-2018101419271931496985

Rights: Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 15.08.2025, 7:28 AM CEST

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Associated

Svahn, Adam J.
Don, Emily K.
Badrock, Andrew P.
Cole, Nicholas J.
Graeber, Manuel B.
Yerbury, Justin J.
Chung, Roger
Morsch, Marco
SpringerLink (Online service)

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Nucleo-cytoplasmic transport of TDP-43 studied in real time: impaired microglia function leads to axonal spreading of TDP-43 in degenerating motor neurons

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Other Objects (12)

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Progranulin reduces insoluble TDP-43 levels, slows down axonal degeneration and prolongs survival in mutant TDP-43 mice

Disease‐linked TDP‐43 hyperphosphorylation suppresses TDP‐43 condensation and aggregation

The effect of TDP-43 antibodies on TDP-43 aggregation and toxicity

TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD

Antibody against TDP-43 phosphorylated at serine 375 suggests conformational differences of TDP-43 aggregates among FTLD–TDP subtypes

Evidence of cerebellar TDP-43 loss of function in FTLD-TDP

Aggregation-prone TDP-43 sequesters and drives pathological transitions of free nuclear TDP-43

Rodent Models of TDP-43 Proteinopathy: Investigating the Mechanisms of TDP-43-Mediated Neurodegeneration

Heteromeric amyloid filaments of ANXA11 and TDP-43 in FTLD-TDP type C

Spreading of TDP-43 pathology via pyramidal tract induces ALS-like phenotypes in TDP-43 transgenic mice

Cytotoxic immune cells do not affect TDP-43 and p62 sarcoplasmic aggregation but influence TDP-43 localisation

SUMOylation Regulates TDP-43 Splicing Activity and Nucleocytoplasmic Distribution

Progranulin reduces insoluble TDP-43 levels, slows down axonal degeneration and prolongs survival in mutant TDP-43 mice

Disease‐linked TDP‐43 hyperphosphorylation suppresses TDP‐43 condensation and aggregation

The effect of TDP-43 antibodies on TDP-43 aggregation and toxicity

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Antibody against TDP-43 phosphorylated at serine 375 suggests conformational differences of TDP-43 aggregates among FTLD–TDP subtypes

Evidence of cerebellar TDP-43 loss of function in FTLD-TDP

Aggregation-prone TDP-43 sequesters and drives pathological transitions of free nuclear TDP-43

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Heteromeric amyloid filaments of ANXA11 and TDP-43 in FTLD-TDP type C

Spreading of TDP-43 pathology via pyramidal tract induces ALS-like phenotypes in TDP-43 transgenic mice

Cytotoxic immune cells do not affect TDP-43 and p62 sarcoplasmic aggregation but influence TDP-43 localisation

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Progranulin reduces insoluble TDP-43 levels, slows down axonal degeneration and prolongs survival in mutant TDP-43 mice

Disease‐linked TDP‐43 hyperphosphorylation suppresses TDP‐43 condensation and aggregation

The effect of TDP-43 antibodies on TDP-43 aggregation and toxicity

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Antibody against TDP-43 phosphorylated at serine 375 suggests conformational differences of TDP-43 aggregates among FTLD–TDP subtypes

Evidence of cerebellar TDP-43 loss of function in FTLD-TDP

Aggregation-prone TDP-43 sequesters and drives pathological transitions of free nuclear TDP-43

Rodent Models of TDP-43 Proteinopathy: Investigating the Mechanisms of TDP-43-Mediated Neurodegeneration

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Cytotoxic immune cells do not affect TDP-43 and p62 sarcoplasmic aggregation but influence TDP-43 localisation

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