Concise One-pot MCRs approach to monofluorinated spiro-pyrazole-pyridine derivatives without additional catalyst
Monofluorinated bis-heterocyclic spirocycles: functionalized ethyl 9-fluoro-8-methyl-1,4-dioxo-2,3,6,10-tetraphenyl-2,3,7-triazaspiro [4.5]dec-7-ene-9-carboxylate derivatives were efficiently synthesized from readily available 1,2-diphenylpyrazolidine-3,5-dione, ethyl 2-fluoroacetoacetate, aromatic aldehyde and ammonium acetate via one-pot four-component reactions in the absence of additional catalyst. In this protocols, ammonium acetate served not only as the fourth component but also as the catalyst. The structures of product were determined by spectral methods and X-ray diffraction analysis.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Concise One-pot MCRs approach to monofluorinated spiro-pyrazole-pyridine derivatives without additional catalyst ; day:01 ; month:06 ; year:2022
SynOpen ; (01.06.2022)
- Beteiligte Personen und Organisationen
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Liu, Ying
Zhang, Yiping
Zhou, Yingkai
Zhang, Min
Deng, Hongmei
Song, Liping
- DOI
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10.1055/a-1866-4653
- URN
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urn:nbn:de:101:1-2022071412423902891249
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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2025-08-15T07:24:53+0200
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Beteiligte
- Liu, Ying
- Zhang, Yiping
- Zhou, Yingkai
- Zhang, Min
- Deng, Hongmei
- Song, Liping
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