100 Years of Thrombotic Thrombocytopenic Purpura: A Story of Death and Life
Abstract: One hundred years ago, in 1924, the first description of a patient with a disease, now known as thrombotic thrombocytopenic purpura (TTP) was published by Dr. Eli Moschcowitz. In honor of this report, this article, written by distinguished specialists in TTP, reviews the increase in scientific knowledge on this disease during the last 100 years. It covers the scientific progress from plasma therapy, the first beneficial treatment for TTP, to the elucidation of the pathophysiology, the discovery of ADAMTS13, the development of assays and targeted therapies up to the modern treatment concepts, that improved the outcome of TTP from an incurable disease to a well understood and treatable disorder.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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100 Years of Thrombotic Thrombocytopenic Purpura: A Story of Death and Life ; volume:44 ; number:01 ; year:2024 ; pages:059-073
Hämostaseologie ; 44, Heft 01 (2024), 059-073
- Contributor
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Lämmle, Bernhard
Vanhoorelbeke, Karen
Kremer Hovinga, Johanna A.
Knöbl, Paul
- DOI
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10.1055/a-2223-9484
- URN
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urn:nbn:de:101:1-2404181014506.535746030448
- Rights
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Kein Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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14.08.2025, 10:57 AM CEST
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Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Lämmle, Bernhard
- Vanhoorelbeke, Karen
- Kremer Hovinga, Johanna A.
- Knöbl, Paul
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Prognostic factors in thrombotic thrombocytopenic purpura
Inherited thrombotic thrombocytopenic purpura mimicking immune thrombocytopenic purpura during pregnancy: a case report
Thrombotic Thrombocytopenic Purpura: A - M: Band 1
Thrombotic Thrombocytopenic Purpura: A - M: Band 2
Graves disease-induced thrombotic thrombocytopenic purpura: a case report
Concurrence of immune thrombocytopenic purpura and thrombotic thrombocytopenic purpura: a case report and review of the literature
Thrombotic thrombocytopenic purpura (TTP)-like syndrome in the HIV era
Thrombotic Thrombocytopenic Purpura
Thrombotic thrombocytopenic purpura
Thrombotic thrombocytopenic purpura
Thrombotic Microangiopathies, Thrombotic Thrombocytopenic Purpura, and ADAMTS-13
Ipilimumab-induced thrombotic thrombocytopenic purpura (TTP)
Prognostic factors in thrombotic thrombocytopenic purpura
Inherited thrombotic thrombocytopenic purpura mimicking immune thrombocytopenic purpura during pregnancy: a case report
Thrombotic Thrombocytopenic Purpura: A - M: Band 1
Thrombotic Thrombocytopenic Purpura: A - M: Band 2
Graves disease-induced thrombotic thrombocytopenic purpura: a case report
Concurrence of immune thrombocytopenic purpura and thrombotic thrombocytopenic purpura: a case report and review of the literature