Sex and Socioeconomic Disparities in Dementia Risk: A Population-Attributable Fraction Analysis in Argentina

Abstract: Introduction: Twelve modifiable risk factors (RFs) account for 40% of dementia cases worldwide. However, limited data exist on such factors in middle- and low-income countries. We aimed to estimate the population-attributable fractions (PAFs) for the 12 RFs in Argentina, assessing changes over a decade and exploring socioeconomic and sex influences. Methods: We conducted cross-sectional analyses of the 12 RFs from Argentinian surveys conducted in 2009, 2015, and 2018, including 96,321 people. We calculated PAFs and stratified estimates based on sex and income. Results: We estimated an overall PAF of 59.6% (95% CI = 58.9–60.3%). The largest PAFs were hypertension = 9.3% (8.7–9.9%), physical inactivity = 7.4% (6.8–8.2%), and obesity = 7.4% (6.8–7.9%). Men were more impacted by excessive alcohol, while women by isolation and smoking. Lower income linked to higher PAFs in education, hypertension, and obesity. Discussion: Argentina has a higher PAF for dementia than the world population, with distinct RF distribution. PAF varied by sex and economic status, advocating tailored prevention strategies.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Sex and Socioeconomic Disparities in Dementia Risk: A Population-Attributable Fraction Analysis in Argentina ; volume:58 ; number:4 ; year:2024 ; pages:264-275 ; extent:12
Neuroepidemiology ; 58, Heft 4 (2024), 264-275 (gesamt 12)

Urheber
Calandri, Ismael Luis
Livingston, Gill
Paradela, Regina
Ossenkoppele, Rik
Crivelli, Lucia
Allegri, Ricardo F.
Suemoto, Claudia K.

DOI
10.1159/000536524
URN
urn:nbn:de:101:1-2408150102517.731010176904
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
14.08.2025, 10:56 MESZ

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Beteiligte

  • Calandri, Ismael Luis
  • Livingston, Gill
  • Paradela, Regina
  • Ossenkoppele, Rik
  • Crivelli, Lucia
  • Allegri, Ricardo F.
  • Suemoto, Claudia K.

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