Artificial intelligence in the NICU to predict extubation success in prematurely born infants

Objectives: Mechanical ventilation in prematurely born infants, particularly if prolonged, can cause long term complications including bronchopulmonary dysplasia. Timely extubation then is essential, yet predicting its success remains challenging. Artificial intelligence (AI) may provide a potential solution. Content: A narrative review was undertaken to explore AI’s role in predicting extubation success in prematurely born infants. Across the 11 studies analysed, the range of reported area under the receiver operator characteristic curve (AUC) for the selected prediction models was between 0.7 and 0.87. Only two studies implemented an external validation procedure. Comparison to the results of clinical predictors was made in two studies. One group reported a logistic regression model that outperformed clinical predictors on decision tree analysis, while another group reported clinical predictors outperformed their artificial neural network model (AUCs: ANN 0.68 vs. clinical predictors 0.86). Amongst the studies there was an heterogenous selection of variables for inclusion in prediction models, as well as variations in definitions of extubation failure. Summary: Although there is potential for AI to enhance extubation success, no model’s performance has yet surpassed that of clinical predictors. Outlook: Future studies should incorporate external validation to increase the applicability of the models to clinical settings.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Artificial intelligence in the NICU to predict extubation success in prematurely born infants ; volume:52 ; number:2 ; year:2024 ; pages:119-125 ; extent:07
Journal of perinatal medicine ; 52, Heft 2 (2024), 119-125 (gesamt 07)

Creator
Jenkinson, Allan C.
Dassios, Theodore
Greenough, Anne

DOI
10.1515/jpm-2023-0454
URN
urn:nbn:de:101:1-2024020813094694238543
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:35 AM CEST

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