Synthesis of 1,2,3 triazole-linked benzimidazole through a copper-catalyzed click reaction

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Abstract: An efficient method has been developed for the synthesis of 1,2,3 triazole-linked benzimidazole through a copper-catalyzed click reaction in ethanol at 50°C. A broad range of aromatic azides were successfully reacted with n-propynylated benzimidazole via copper-catalyzed azide-alkyne cycloaddition reactions in the absence of a ligand. This method offers many advantages including short reaction times, low cost, and simple purification procedures.

Location: Deutsche Nationalbibliothek Frankfurt am Main

Extent: Online-Ressource

Language: Englisch

Bibliographic citation: Synthesis of 1,2,3 triazole-linked benzimidazole through a copper-catalyzed click reaction ; volume:25 ; number:1 ; year:2019 ; pages:122-129 ; extent:8
Heterocyclic communications ; 25, Heft 1 (2019), 122-129 (gesamt 8)

Creator: Bakherad, Mohammad
Keivanloo, Ali
Amin, Amir H.
Farkhondeh, Amir

DOI: 10.1515/hc-2019-0016

URN: urn:nbn:de:101:1-2501130632390.668468935448

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 02.08.2025, 7:32 AM CEST

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Bakherad, Mohammad
Keivanloo, Ali
Amin, Amir H.
Farkhondeh, Amir

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Synthesis of 1,2,3 triazole-linked benzimidazole through a copper-catalyzed click reaction

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Other Objects (12)

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Asymmetric Copper-Catalyzed Defluoroalkylation

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