Strategies for Exploring Functions from Dynamic Combinatorial Libraries
Abstract: Dynamic combinatorial chemistry (DCC) is a powerful approach for creating complex chemical systems, giving access to the studies of complexity and exploration of functionality in synthetic systems. However, compared with more advanced living systems, the man‐made chemical systems are still less functional, due to their limited complexity and insufficient kinetic control. Here we start by introducing strategies to enrich the complexity of dynamic combinatorial libraries (DCLs) for exploiting unexpected functions by increasing the species of building blocks and/or templates used. Then, we discuss how dynamic isomerization of photo‐switchable molecules help DCLs increase and alter the systemic complexity in‐situ. Multi‐phase DCLs will also be reviewed to thrive complexity and functionality across the interfaces. Finally, there will be a summary and outlook about remote kinetic control in DCLs that are realized by applying exogenous physical transduction signals of stress, light, heat and ultrasound.
- Standort
-
Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
-
Online-Ressource
- Sprache
-
Englisch
- Erschienen in
-
Strategies for Exploring Functions from Dynamic Combinatorial Libraries ; volume:2 ; number:5 ; year:2020 ; extent:10
ChemSystemsChem ; 2, Heft 5 (2020) (gesamt 10)
- Urheber
-
Jia, Chunman
Qi, Dawei
Zhang, Yucang
Rissanen, Kari
Li, Jianwei
- DOI
-
10.1002/syst.202000019
- URN
-
urn:nbn:de:101:1-2022070108003621869979
- Rechteinformation
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
-
15.08.2025, 07:36 MESZ
Datenpartner
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Jia, Chunman
- Qi, Dawei
- Zhang, Yucang
- Rissanen, Kari
- Li, Jianwei
Ähnliche Objekte (12)
DNA-encoded dynamic combinatorial chemical libraries
Fuel‐Driven Dynamic Combinatorial Peptide Libraries
Combinatorial peptide and nonpeptide libraries : a handbook
Combinatorial libraries : synthesis, screening and application potential
Chemically Fueled Dynamic Combinatorial Libraries : Towards Synthetic Life
Solid Support Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries
Combinatorial Libraries of Bipodal Binders of the Insulin Receptor
Analytical Tools for Dynamic Combinatorial Libraries of Cyclic Peptides
Combinatorial Analysis of Silver‐Palladium Alloy Thin Film Libraries
Template-based copying in chemically fuelled dynamic combinatorial libraries
Exploring HIV-1 - Host Cell Interactions using Peptides derived from Human Pegivirus-1, and from Combinatorial Libraries
Autocatalytic desymmetrization of prochiral compounds : strategies to dictate and control self-replication in peptidic dynamic combinatorial libraries
DNA-encoded dynamic combinatorial chemical libraries
Fuel‐Driven Dynamic Combinatorial Peptide Libraries
Combinatorial peptide and nonpeptide libraries : a handbook
Combinatorial libraries : synthesis, screening and application potential
Chemically Fueled Dynamic Combinatorial Libraries : Towards Synthetic Life
Solid Support Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries
Combinatorial Libraries of Bipodal Binders of the Insulin Receptor
Analytical Tools for Dynamic Combinatorial Libraries of Cyclic Peptides
Combinatorial Analysis of Silver‐Palladium Alloy Thin Film Libraries
Template-based copying in chemically fuelled dynamic combinatorial libraries
Exploring HIV-1 - Host Cell Interactions using Peptides derived from Human Pegivirus-1, and from Combinatorial Libraries
Autocatalytic desymmetrization of prochiral compounds : strategies to dictate and control self-replication in peptidic dynamic combinatorial libraries
DNA-encoded dynamic combinatorial chemical libraries
Fuel‐Driven Dynamic Combinatorial Peptide Libraries
Combinatorial peptide and nonpeptide libraries : a handbook
Combinatorial libraries : synthesis, screening and application potential
Chemically Fueled Dynamic Combinatorial Libraries : Towards Synthetic Life
Solid Support Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries
Combinatorial Libraries of Bipodal Binders of the Insulin Receptor
Analytical Tools for Dynamic Combinatorial Libraries of Cyclic Peptides
Combinatorial Analysis of Silver‐Palladium Alloy Thin Film Libraries
Template-based copying in chemically fuelled dynamic combinatorial libraries
Exploring HIV-1 - Host Cell Interactions using Peptides derived from Human Pegivirus-1, and from Combinatorial Libraries