Advancing SARS‐CoV‐2 Variant Detection with High Affinity Monoclonal Antibodies and Plasmonic Nanostructure
Abstract: A nanoplasmonic biosensor for the precise detection of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) by leveraging advances in nanostructured sensing materials and highly selective monoclonal antibodies is presented. The sensor integrates plasmonic Au nanostructures optimized for surface‐enhanced Raman scattering (SERS), enhancing sensitivity through unique light interactions at the nanoscale. Coupled with exclusive antibodies that specifically target SARS‐CoV‐2 and its evolving variants, this sensor demonstrates remarkable selectivity and versatility. Validated with 270 clinical samples, it demonstrates a sensitivity of 98.9% and specificity of 100%. More importantly, the virus in nasopharyngeal swab samples collected over 3 years, marking the long‐term, large‐scale clinical validation of the nanoplasmonic biosensor for SARS‐CoV‐2 is been successfully detected. Furthermore, the integration of this sensor with face masks enables the detection of airborne SARS‐CoV‐2, highlighting its potential for routine management of coronavirus disease 2019 (COVID‐19).
- Standort
-
Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
-
Online-Ressource
- Sprache
-
Englisch
- Erschienen in
-
Advancing SARS‐CoV‐2 Variant Detection with High Affinity Monoclonal Antibodies and Plasmonic Nanostructure ; day:16 ; month:09 ; year:2024 ; extent:11
Advanced functional materials ; (16.09.2024) (gesamt 11)
- Urheber
-
Ryu, Jea Sung
Lee, Soo Hyun
Kim, Hyeran
Kang, Hyunju
Li, Pei
Lee, Joo Hoon
Jang, Hyowon
Kim, Sunjoo
Kwon, Hyung‐Jun
Jung, Ho Sang
Jung, Yongwon
Lim, Eun‐Kyung
Jung, Juyeon
Park, Sung‐Gyu
Kang, Taejoon
- DOI
-
10.1002/adfm.202405340
- URN
-
urn:nbn:de:101:1-2409161415057.384877710821
- Rechteinformation
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
-
15.08.2025, 07:35 MESZ
Datenpartner
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Ryu, Jea Sung
- Lee, Soo Hyun
- Kim, Hyeran
- Kang, Hyunju
- Li, Pei
- Lee, Joo Hoon
- Jang, Hyowon
- Kim, Sunjoo
- Kwon, Hyung‐Jun
- Jung, Ho Sang
- Jung, Yongwon
- Lim, Eun‐Kyung
- Jung, Juyeon
- Park, Sung‐Gyu
- Kang, Taejoon
Ähnliche Objekte (12)
The Contemporary Significance of Gibran’s Literary Works
Bio-inspired computation in unmanned aerial vehicle
Multielectron Transfer in Halogen Batteries
On the Effectiveness and Externalities of the Home Purchase Restriction Policy in China
Fiscal Pressure, Inter-Industrial Allocation of Land and Agglomerations Effects
Use of Real-World Evidence in Regulatory Decisions for Traditional Chinese Medicine: Current Status and Future Directions
Concomitant double-fusion of PLEKHA7-ALK and INPP5D-ALK reveals favorable alectinib sensitivity in lung adenocarcinoma: a case report and literature review
Therapeutic effects of human gingiva-derived mesenchymal stromal cells on murine contact hypersensitivity via prostaglandin E2–EP3 signaling
Dynamics of water eutrophication model with control
Comparing the influence of visual information and the perceived intelligence of voice assistants when shopping for sustainable clothing online
Evolutionary dynamics of the severe acute respiratory syndrome coronavirus 2 genomes
Detecting breakpoints in global temperature
The Contemporary Significance of Gibran’s Literary Works
Bio-inspired computation in unmanned aerial vehicle
Multielectron Transfer in Halogen Batteries
On the Effectiveness and Externalities of the Home Purchase Restriction Policy in China
Fiscal Pressure, Inter-Industrial Allocation of Land and Agglomerations Effects
Use of Real-World Evidence in Regulatory Decisions for Traditional Chinese Medicine: Current Status and Future Directions
Concomitant double-fusion of PLEKHA7-ALK and INPP5D-ALK reveals favorable alectinib sensitivity in lung adenocarcinoma: a case report and literature review
Therapeutic effects of human gingiva-derived mesenchymal stromal cells on murine contact hypersensitivity via prostaglandin E2–EP3 signaling
Dynamics of water eutrophication model with control
Comparing the influence of visual information and the perceived intelligence of voice assistants when shopping for sustainable clothing online
Evolutionary dynamics of the severe acute respiratory syndrome coronavirus 2 genomes
Detecting breakpoints in global temperature
The Contemporary Significance of Gibran’s Literary Works
Bio-inspired computation in unmanned aerial vehicle
Multielectron Transfer in Halogen Batteries
On the Effectiveness and Externalities of the Home Purchase Restriction Policy in China
Fiscal Pressure, Inter-Industrial Allocation of Land and Agglomerations Effects
Use of Real-World Evidence in Regulatory Decisions for Traditional Chinese Medicine: Current Status and Future Directions
Concomitant double-fusion of PLEKHA7-ALK and INPP5D-ALK reveals favorable alectinib sensitivity in lung adenocarcinoma: a case report and literature review
Therapeutic effects of human gingiva-derived mesenchymal stromal cells on murine contact hypersensitivity via prostaglandin E2–EP3 signaling
Dynamics of water eutrophication model with control
Comparing the influence of visual information and the perceived intelligence of voice assistants when shopping for sustainable clothing online
Evolutionary dynamics of the severe acute respiratory syndrome coronavirus 2 genomes