Dual-AAV mediated transfer of full-length otoferlin cDNA into auditory inner hair cells and the effects of different mutations in the OTOF gene on the protein levels and cellular distribution of otoferlin in auditory inner hair cells

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Location: Deutsche Nationalbibliothek Frankfurt am Main

Extent: Online-Ressource

Language: Englisch

Notes: Göttingen, Georg-August Universität, Dissertation, 2019

Keyword: Hair cells
Cochlea
Labyrinth (Ear)
Mice
Gene therapy

Event: Veröffentlichung

(where): Göttingen

(who): Niedersächsische Staats- und Universitätsbibliothek Göttingen

(when): 2019

Creator: Al-Moyed, Hanan

Contributor: Reisinger, Ellen
Brose, Nils
Kügler, Sebastian
Rizzoli, Silvio
Dresbach, Thomas
Thoms, Sven

Handle: 11858/00-1735-0000-002E-E626-E

URN: urn:nbn:de:gbv:7-11858/00-1735-0000-002E-E626-E-9

Rights: Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 14.08.2025, 10:44 AM CEST

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Associated

Al-Moyed, Hanan
Reisinger, Ellen
Brose, Nils
Kügler, Sebastian
Rizzoli, Silvio
Dresbach, Thomas
Thoms, Sven
Niedersächsische Staats- und Universitätsbibliothek Göttingen

Time of origin

2019

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Dual-AAV mediated transfer of full-length otoferlin cDNA into auditory inner hair cells and the effects of different mutations in the OTOF gene on the protein levels and cellular distribution of otoferlin in auditory inner hair cells

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Other Objects (12)

Defects in hair cells disrupt the development of auditory peripheral circuitry

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MSC-derived exosomes protect auditory hair cells from neomycin-induced damage via autophagy regulation

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Simvastatin protects auditory hair cells from gentamicin-induced toxicity and activates Akt signaling in vitro

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Chaotic Dynamics of Inner Ear Hair Cells

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CIB2, defective in isolated deafness, is key for auditory hair cell mechanotransduction and survival

Simvastatin protects auditory hair cells from gentamicin-induced toxicity and activates Akt signaling in vitro

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Telmisartan Protects Auditory Hair Cells from Gentamicin-Induced Toxicity in vitro

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Chaotic Dynamics of Inner Ear Hair Cells

Regulation of cell proliferation and apoptosis by growth hormone during zebrafish auditory hair cell regeneration

Stem Cell-Based Hair Cell Regeneration and Therapy in the Inner Ear

MSC-derived exosomes protect auditory hair cells from neomycin-induced damage via autophagy regulation

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Simvastatin protects auditory hair cells from gentamicin-induced toxicity and activates Akt signaling in vitro

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