Cell dynamics in WOX5-overexpressing root tips: the impact of local auxin biosynthesis
Abstract: Root stem cell niche functioning requires the formation and maintenance of the specific “auxin-rich domain” governed by directional auxin transport and local auxin production. Auxin maximum co-localizes with the WOX5 expression domain in the quiescent center that separates mitotically active proximal and distal root meristems. Here we unravel the interconnected processes happening under WOX5 overexpression by combining in vivo experiments and mathematical modeling. We showed that WOX5-induced TAA1-mediated auxin biosynthesis is the cause, whereas auxin accumulation, PIN transporters relocation, and auxin redistribution between proximal and distal root meristems are its subsequent effects that influence the formation of the well-described phenotype with an enlarged root cap. These findings helped us to clarify the role of WOX5, which serves as a local QC-specific regulator that activates biosynthesis of non-cell-autonomous signal auxin to regulate the distal meristem functioning. The mathematical model with WOX5-mediated auxin biosynthesis and auxin-regulated cell growth, division, and detachment reproduces the columella cells dynamics in both wild type and under WOX5 dysregulation
- Location
-
Deutsche Nationalbibliothek Frankfurt am Main
- Extent
-
Online-Ressource
- Language
-
Englisch
- Notes
-
Frontiers in plant science. - 11 (2020) , 560169, ISSN: 1664-462X
- Event
-
Veröffentlichung
- (where)
-
Freiburg
- (who)
-
Universität
- (when)
-
2021
- Creator
-
Savina, Maria S.
Pasternak, Taras
Omelyanchuk, Nadya A.
Novikova, Daria D.
Palme, Klaus
Mironova, Victoria
Lavrekha, Viktoriya V.
- DOI
-
10.3389/fpls.2020.560169
- URN
-
urn:nbn:de:bsz:25-freidok-2205314
- Rights
-
Kein Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
-
25.03.2025, 1:54 PM CET
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Savina, Maria S.
- Pasternak, Taras
- Omelyanchuk, Nadya A.
- Novikova, Daria D.
- Palme, Klaus
- Mironova, Victoria
- Lavrekha, Viktoriya V.
- Universität
Time of origin
- 2021
Other Objects (12)
Glutathione enhances auxin sensitivity in Arabidopsis roots
Root-specific expression of early auxin-regulated
Arabidopsis NITRILASE 1 contributes to the regulation of root growth and development through modulation of Auxin biosynthesis in seedlings
Polar auxin transport and auxin induced development : root system and signaling molecules give the clue
Polar Auxin Transport Determines Adventitious Root Emergence and Growth in Rice
Distinct auxin signalling hubs modulate secondary growth and shape root architectures
The role of auxin biosynthesis during leaf vein initiation and patterning in Arabidopsis
Review: Local roots revisited
The underground tango: how ethylene and auxin interact to regulate cereal root angle
Auxin steers root cell expansion via apoplastic pH regulation in Arabidopsis thaliana
Aluminum Stress on Suberin Biosynthesis in Barley (Hordeum vulgare) Roots
Suberin biosynthesis in barley roots in response to osmotic stress
Glutathione enhances auxin sensitivity in Arabidopsis roots
Root-specific expression of early auxin-regulated
Arabidopsis NITRILASE 1 contributes to the regulation of root growth and development through modulation of Auxin biosynthesis in seedlings
Polar auxin transport and auxin induced development : root system and signaling molecules give the clue
Polar Auxin Transport Determines Adventitious Root Emergence and Growth in Rice
Distinct auxin signalling hubs modulate secondary growth and shape root architectures
The role of auxin biosynthesis during leaf vein initiation and patterning in Arabidopsis
Review: Local roots revisited
The underground tango: how ethylene and auxin interact to regulate cereal root angle
Auxin steers root cell expansion via apoplastic pH regulation in Arabidopsis thaliana
Aluminum Stress on Suberin Biosynthesis in Barley (Hordeum vulgare) Roots
Suberin biosynthesis in barley roots in response to osmotic stress
Glutathione enhances auxin sensitivity in Arabidopsis roots
Root-specific expression of early auxin-regulated
Arabidopsis NITRILASE 1 contributes to the regulation of root growth and development through modulation of Auxin biosynthesis in seedlings
Polar auxin transport and auxin induced development : root system and signaling molecules give the clue
Polar Auxin Transport Determines Adventitious Root Emergence and Growth in Rice
Distinct auxin signalling hubs modulate secondary growth and shape root architectures
The role of auxin biosynthesis during leaf vein initiation and patterning in Arabidopsis
Review: Local roots revisited
The underground tango: how ethylene and auxin interact to regulate cereal root angle
Auxin steers root cell expansion via apoplastic pH regulation in Arabidopsis thaliana
Aluminum Stress on Suberin Biosynthesis in Barley (Hordeum vulgare) Roots