Endoscopic Ultrasound-Guided Liver Biopsy (EUS-LB): An Endoscopic Solution to the Unmet Needs of Liver Tissue Acquisition and Beyond

Abstract: Aim and Objective Endoscopic ultrasound-guided liver biopsy (EUS-LB) is now increasingly being used across the globe as a method of liver tissue acquisition. This method is widely accepted by many professionals as it can overcome many shortcomings of percutaneous liver biopsy and transjugular liver biopsy. The aim of the study is to obtain the adequate and optimal biopsy rate associated with EUS-LB. Materials and Methods This is a retrospective observational study. Consecutive patients undergoing EUS-LB during the study period who were willing to consent were taken up for the study. Results Total 91 patients were taken up for the study. Median age of study population was 44 years out of which 39 patients were males and 52 were females (42.9 and 57.1%). Adequate biopsy rate (according to European Association for the Study of Liver Disease criteria) and optimal biopsy rate (according to American Association for the Study of Liver Diseases criteria) were 89 (81/91) and 60.4% (55/91), respectively. Rate of conclusive diagnosis was 95.6% (86/91). The commonest diagnosis encountered was nonalcoholic steatohepatitis) (23, 25.3%), followed by autoimmune hepatitis (17, 18.7%). Additional diagnostic information was obtained by endosonography during EUS-LB in 21 patients (23.1%). Gallstone disease was found in four (4.8%) patients, chronic calcific pancreatitis in two (1.9%) patients, significant abdominal lymphadenopathy defined as lymph node more than 1.5 cm in five (5.8%) patients, and esophageal or gastric varices in ten (10.6%) patients. One case of self-limiting biopsy site ooze was seen in EUS-LB and the patient was having cirrhosis. Conclusion This study showed a high diagnostic outcome and safety profile with EUS-LB technique. EUS-LB can achieve excellent histological yield when performed with optimal technique. Moreover, it is possible to obtain additional information during the procedure from diagnostic endosonography that is done as a part of EUS-LB.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Endoscopic Ultrasound-Guided Liver Biopsy (EUS-LB): An Endoscopic Solution to the Unmet Needs of Liver Tissue Acquisition and Beyond ; volume:15 ; number:02 ; year:2024 ; pages:110-115
Journal of Digestive Endoscopy ; 15, Heft 02 (2024), 110-115

Beteiligte Personen und Organisationen
Khare, Shivam
Arora, Anil
Varghese, Jijo
Kumar, Ashish
Jain, Sunila
Khandelwal, Ashiesh
Mittal, Arpita
Misra, Sunayana
Anikhindi, Shrihari
Kumar, Mandhir
Ranjan, Piyush
Sharma, Praveen
Bansal, Naresh
Sachdeva, Munish
Giri, Suprabhat
S., Srijaya

DOI
10.1055/s-0044-1785498
URN
urn:nbn:de:101:1-2408081223013.822264559375
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
14.08.2025, 11:03 MESZ

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Beteiligte

  • Khare, Shivam
  • Arora, Anil
  • Varghese, Jijo
  • Kumar, Ashish
  • Jain, Sunila
  • Khandelwal, Ashiesh
  • Mittal, Arpita
  • Misra, Sunayana
  • Anikhindi, Shrihari
  • Kumar, Mandhir
  • Ranjan, Piyush
  • Sharma, Praveen
  • Bansal, Naresh
  • Sachdeva, Munish
  • Giri, Suprabhat
  • S., Srijaya

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