Caesarean delivery during dual antiplatelet therapy after acute myocardial infarction and stenting

Background: Cardiac disease is the leading cause of maternal mortality during pregnancy in high-resource countries. Case: A 31-year-old woman had an ST-elevated myocardial infarction (STEMI) at 16 gestational weeks. The patient received three coronary drug-eluting stents followed by dual antiplatelet therapy (DAPT) with aspirin and clopidogrel. An elective caesarean delivery was performed under general anesthesia at 37+1 gestational weeks. Due to subnormal response to clopidogrel, administration was paused only 24 h perioperatively without bridging with tirofiban because of the slightly increased risk of stent thrombosis in clopidogrel nonresponders. There was no postoperative bleeding. Conclusions: There is a lack of evidence-based guidelines regarding the management of acute myocardial infarction (AMI) during pregnancy; thus, delivery should be performed in a tertiary center with a multidisciplinary approach.

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Caesarean delivery during dual antiplatelet therapy after acute myocardial infarction and stenting ; volume:6 ; number:2 ; year:2017 ; extent:4 ; Case reports in perinatal medicine ; 6, Heft 2 (2017) (gesamt 4)

Contributors, Places and Time

• Creator: Vitezica, Irena ; von Heymann, Christian ; Henrich, Wolfgang ; Bamberg, Christian

Further information

• DOI: 10.1515/crpm-2017-0002
• URN: urn:nbn:de:101:1-2411121519280.591668794707
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 15.08.2025, 7:25 AM CEST