Arbeitspapier

A statistical framework for the analysis of multivariate infectious disease surveillance data

A framework for the statistical analysis of counts from infectious disease surveillance database is proposed. In its simplest form, the model can be seen as a Poisson branching process model with immigration. Extensions to include seasonal effects, time trends and overdispersion are outlined. The model is shown to provide an adequate fit and reliable one-step-ahead prediction intervals for a typical infectious disease surveillance time series. Furthermore, a multivariate formulation is proposed, which is well suited to capture space-time interactions caused by the spatial spread of a disease over time. analyses of uni- and multivariate times series on several infectious diseases are described. All analyses have been done using general optimization routines where ML estimates and corresponding standard errors are readily available.

Language
Englisch

Bibliographic citation
Series: Discussion Paper ; No. 402

Subject
Branching Process with Immigration
Infectious Disease Surveillance
Maximum Likelihood
Multivariate Time Series of Counts
Observation-driven
Parameter-driven
Space-Time-Models

Event
Geistige Schöpfung
(who)
Held, Leonhard
Höhle, Michael
Hofmann, Mathias
Event
Veröffentlichung
(who)
Ludwig-Maximilians-Universität München, Sonderforschungsbereich 386 - Statistische Analyse diskreter Strukturen
(where)
München
(when)
2004

DOI
doi:10.5282/ubm/epub.1772
Handle
URN
urn:nbn:de:bvb:19-epub-1772-2
Last update
10.03.2025, 11:42 AM CET

Data provider

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Object type

  • Arbeitspapier

Associated

  • Held, Leonhard
  • Höhle, Michael
  • Hofmann, Mathias
  • Ludwig-Maximilians-Universität München, Sonderforschungsbereich 386 - Statistische Analyse diskreter Strukturen

Time of origin

  • 2004

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